Results 71 to 80 of about 615,598 (259)

Magnetic Resonance Imaging of the Neonatal Brain: Modalities, Scoring Systems, and Clinical Applications

Bioengineering
Magnetic resonance imaging (MRI) has become the gold standard for evaluating brain injury and development in newborn infants, providing structural, metabolic, and functional information without ionizing radiation. This review comprehensively examines the
Swathi Ariyapadi, Emily Garavatti, Terrie Inder   +2 more
doaj   +1 more source

Cross sectional, community based study of care of newborn infants in Nepal [PDF]

, 2002
Objective To determine home based newborn care practices in rural Nepal in order to inform strategies to improve neonatal outcome.Design Cross sectional, retrospective study using structured interviews.Setting Makwanpur district, Nepal.Participants 5411 ...
Osrin, D, Shtestha, BP, Costello, AMD, Tumbahangphe, KM, Manandhar, DS, Manandhar, MK, Standing, H, Shrestha, D, Mesko, N   +8 more
core  

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Insights into Neonatal Oral Feeding through the Salivary Transcriptome

International Journal of Pediatrics, 2012
Background. The development of safe and effective oral feeding skills in the newborn is complex and may be associated with significant morbidities. Our understanding of neonatal oral feeding maturation at the molecular level is limited, providing an ...
Jill L. Maron
doaj   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

SKIN CARE IN YOUNG CHILDREN: INNOVATIVE APPROACHES

Медицинский совет, 2018
The article presents modern data on the ontogenesis of the skin, the formation of all its elements and structures during prenatal development and postnatal period. The modern ideas about the features of the structure of the skin in the newborn and infant
I. N. Zakharova, A. N. Kasyanova, E. B. Machneva   +2 more
doaj   +1 more source

Postnatal infant crying and maternal tiredness : examining their evolution and interaction in the first 12 weeks postpartum [PDF]

, 2010
A new mother lazing in childbed is a blessing for her family” is an old Swiss proverb. Maternal rest and recuperation after birth was a common concern in the past and was frequently supported by the extended family.
Kurth, Elisabeth
core   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

The effect of maternal common mental disorders on infant undernutrition in Butajira, Ethiopia: the P-MaMiE study. [PDF]

, 2010
BACKGROUND: Although maternal common mental disorder (CMD) appears to be a risk factor for infant undernutrition in South Asian countries, the position in sub-Saharan Africa (SSA) is unclear METHODS: A population-based cohort of 1065 women, in the third ...
Mark Tomlinson, Vikram Patel, Prince Martin, Atalay Alem, Fikru Tesfaye, Mesfin Aray, Worku Bogale, Tomlinson Mark, Abdulahi, Abdulreshid, Abdulahi Abdulreshid, Medhin, Girmay, Zufan Lakew, Abdulreshid Abdulahi, Marcus Hughes, Lakew Zufan, Charlotte Hanlon, Bogale Worku, Worku, Bogale, Alem, Atalay,, Hughes Marcus, Martin Prince, Prince, Martin, Lakew, Zufan, Hanlon Charlotte, Aray, Mesfin, Dewey Michael, Michael Dewey, Alem Atalay, Tesfaye, Fikru, Patel Vikram, Dewey, Michael, Alem, Atalay, Aray Mesfin, Patel, Vikram, Hanlon, Charlotte, Tesfaye Fikru, Hughes, Marcus, Girmay Medhin, Medhin Girmay, Tomlinson, Mark   +39 more
core   +2 more sources

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source