Results 41 to 50 of about 368,219 (263)

Childbirth and motherhood in women with motor disability due to a rare condition: an exploratory study

Orphanet Journal of Rare Diseases, 2021
Background Rare diseases may result in motor impairment, which in turn may affect parenthood. Our purpose was to evaluate perinatal outcomes, parenting needs, mother-infant interactions and infant development in a set of volunteer women with motor ...
Marc Dommergues, Drina Candilis, Ludivine Becerra, Edith Thoueille, David Cohen, Sylvie Viaux-Savelon   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Low prevalence of infantile functional gastrointestinal disorders (FGIDs) in a multi-ethnic Asian population

Pediatrics and Neonatology, 2021
Background: Functional gastrointestinal disorders (FGIDs) are common in children. The prevalence of FGIDs varies across the world but is unknown in Malaysia. We aimed to investigate the prevalence of FGIDs in healthy Malaysian infants.
Kee Seang Chew, Jun Min Em, Zhong Lin Koay, Muhammad Yazid Jalaludin, Ruey Terng Ng, Lucy Chai See Lum, Way Seah Lee   +6 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Bridging the gap: family resilience as a mediator between parental psychological resilience and care competence in premature infant transitions

BMC Psychology
Background High levels of parental infant care competence could facilitate the transition of preterm infants from hospital to home and reduce their readmission rate and emergency visits after discharge. Researchers have confirmed psychological resilience
Chengxi Zeng, Jianlin Ji, Hanlin Yang, Liling Yang, Yan Jiang, Ping Tang, Qunfeng Lu   +6 more
doaj   +1 more source

The Disease Spectrum and Influencing Factors of NICU in Xiangxi, Underdeveloped Area of China: A 9-Year Retrospective Study

Frontiers in Pediatrics, 2022
ObjectiveInvestigation of the basic conditions and disease spectrum in neonatal intensive care unit (NICU) from 2012 to 2020, in the underdeveloped area of Xiangxi, China.MethodsAll newborns (N = 16,094) admitted to the NICU of a hospital in the Xiangxi ...
Fen Xie, Fen Xie, Yuhua Zhu, Yuhua Zhu, Lulu Chen, Lulu Chen, Ruyi Han, Ruyi Han, Qingxia Shu, Zheng-ying Chen, Jinxiu Li   +10 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Severe haemophilia A in a preterm girl with Turner syndrome: case report – a diagnostic and therapeutic challenge for a paediatrician (Part 2)

Italian Journal of Pediatrics, 2021
Background Haemophilia A is an X-linked genetic condition which manifests itself mainly in male children in the first 2 years of life, during gross motor skill development. This disorder is rare in females.
Berendt Agnieszka, Wójtowicz-Marzec Monika, Wysokińska Barbara, Kwaśniewska Anna   +3 more
doaj   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Intra-uterine Growth Retardation and Development of Hypertension

Acta Medica Indonesiana, 2017
Low birth weight (LBW) is defined as a birth weight of a liveborn infant of
Haerani Rasyid, Syakib Bakri
doaj   +2 more sources