Results 21 to 30 of about 126,231 (300)

AnAlysis oF treAtment in pAtients With inFAntile hemAnGiomA in the depArtment oF pediAtriC otolArynGoloGy, mediCAl UniVersity oF WArsAW [PDF]

New Medicine, 2016
Introduction. infantile hemangiomas in the region of head and neck are relatively common. When localized in the vicinity ofvital organs, airways or the eye, they may cause a serious threat to the child’s health and development, or even life.
Piotr Kwast, Monika Jabłońska-Jesionowska, lidia Zawadzka-głos   +2 more
doaj   +1 more source

Noninferiority and Safety of Nadolol vs Propranolol in Infants With Infantile Hemangioma

JAMA pediatrics, 2021
Key Points Question Is nadolol noninferior to propranolol in the management of infantile hemangioma? Findings In this randomized clinical trial, infantile hemangiomas treated with nadolol showed a larger change in size and color compared with propranolol,
E. Pope, I. Lara‐Corrales, C. Sibbald, C. Liy-Wong, N. Kanigsberg, B. Drolet, Jin Ma   +6 more
semanticscholar   +1 more source

Oral Beta-blocker in Problematic Infantile Hemangioma

Plastic and Reconstructive Surgery, Global Open, 2021
Summary:. One of the most common benign vascular endothelial tumors is infantile hemangioma. These lesions are commonly found in the head and neck, and sometimes it is a challenge to decide the method of treatment if the lesions are problematic ...
Rashed N. AlHasan, MB, BCh, BAO, Lamees Arabiyat, MD, JBPRS, MCs, Hamad M. Ammar, MBBCH, JBPRS, Nayef A. Louri, MD, ADPS   +3 more
doaj   +1 more source

Success in the use of oral propranolol in the treatment of infantile hemangioma in nasal tip - Report of two cases, [PDF]

Anais Brasileiros de Dermatologia, 2020
Infantile hemangioma is the most common pediatric vascular tumor, with the following risk factors: low birth weight, prematurity, white skin, female gender, multiparity and advanced maternal age. The use of oral and topical beta-blockers, although recent,
Mariana Carvalho Costa, Odil Garrido Campos de Andrade, Lethícia de Castro Pereira, Izelda Maria Carvalho Costa   +3 more
doaj   +1 more source

Critical role of Aquaporin-1 and telocytes in infantile hemangioma response to propranolol beta blockade

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Although a role for β-adrenergic receptor (ADRB) in cancer progression was suggested a long time ago, our serendipitous observation of the propranolol efficacy in treating infantile hemangioma (IH) has driven attention in exploring the ...
F. Moisan, S. Oucherif, P. Kaulanjan-Checkmodine, S. Prey, B. Rousseau, M. Bonneu, S. Claverol, E. Gontier, S. Lacomme, L. Dousset, T. Couffinhal, J. Toutain, M. Loot, M. Cario-André, M. Jullie, C. Léauté-Labrèze, A. Taieb, H. Rezvani   +17 more
semanticscholar   +1 more source

Non–beta blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Journal of Clinical Investigation, 2021
Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are composed of R(+) and S(–) enantiomers: the R(+) enantiomer is largely devoid of beta blocker activity.
C. Seebauer, Matthew S. Graus, Lan Huang, Alex J. McCann, Jill Wylie-Sears, F. Fontaine, T. Karnezis, D. Zurakowski, S. Staffa, F. Meunier, J. Mulliken, J. Bischoff, M. Francois   +12 more
semanticscholar   +1 more source

Efficacy and Safety of Topical Timolol for the Treatment of Infantile Hemangioma in the Early Proliferative Stage: A Randomized Clinical Trial.

JAMA dermatology, 2021
Importance Treatment of infantile hemangioma (IH) with topical timolol in the first 2 months of life (early proliferative phase) may prevent further growth and the need for treatment with oral propranolol.
F. Muñoz-Garza, Mônica Rios, E. Roé-Crespo, J. Bernabéu-Wittel, M. T. Montserrat-García, L. Puig, I. Gich, E. Baselga   +7 more
semanticscholar   +1 more source

Phosphorylated Forms of STAT1, STAT3 and STAT5 Are Expressed in Proliferating but Not Involuted Infantile Hemangioma

Frontiers in Surgery, 2018
We have recently demonstrated the expression of embryonic stem cell markers on the endothelium of infantile hemangioma, a functional hemogenic endothelium with the capacity for primitive erythropoiesis in vitro.
Lucy Sulzberger, Elysia M. S. Tan, Paul F. Davis, Helen D. Brasch, Helen D. Brasch, Swee T. Tan, Swee T. Tan, Tinte Itinteang   +7 more
doaj   +1 more source

Integrative meta-analysis identifies microRNA-regulated networks in infantile hemangioma [PDF]

, 2016
BACKGROUND: Hemangioma is a common benign tumor in the childhood; however our knowledge about the molecular mechanisms of hemangioma development and progression are still limited.
Fábio E. Severino, Lied M. S. Pereira, Natália Bertoni, Patricia P. Reis, Regina Moura, Winston B. Yoshida   +5 more
core   +2 more sources

PHACE syndrome: clinical manifestations, diagnostic criteria, and management [PDF]

Anais Brasileiros de Dermatologia, 2018
: Infantile hemangioma can be linked to other organ malformations. In 1996, PHACE syndrome was first defined as the association of large and segmental infantile hemangioma, usually on the face, head, or cervical region, with malformations of the ...
Anita Rotter, Luciana Paula Samorano, Maria Cecília Rivitti-Machado, Zilda Najjar Prado Oliveira, Bernardo Gontijo   +4 more
doaj   +1 more source