Results 51 to 60 of about 7,433 (164)

Artificial Intelligence Software Changes Rare Disease Testing Strategy in Real Time: An International Case Series Using Face2Gene

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Genetic disorders commonly share features such as developmental delays, cognitive impairment, and behavioral challenges, yet many conditions also present unique dysmorphic features that distinguish them. Performing a thorough medical and family history and a detailed physical exam with attention to dysmorphic features is often the first step ...
Natasha L. Rudy, Adriana Gomes, Tinatin Tkemaladze, Omar Abdul‐Rahman, Drew Cratsenberg, Giulia Pascolini, Giovanni Di Zenzo, Daniele Castiglia, Emily Black, Camerun Washington, Lauren Chad, Cynthia Curry, Miguel Del Campo, Nicole Fleischer, Lynne M. Bird, Anna C. E. Hurst   +15 more
wiley   +1 more source

Infantile periocular hemangioma

Journal of Ophthalmic & Vision Research, 2017
Infantile periocular hemangiomas (IPH) are common benign vascular tumors that present early in childhood. They typically show a rapid nonlinear growth pattern a few weeks after birth during a proliferative phase, then continue with an involution phase ...
Mehdi Tavakoli, Saeid Yadegari, Mahnaz Mosallaei, Maryam Aletaha, Hossein Salour, Wendy W Lee   +5 more
doaj   +1 more source

What's in the pipeline for pediatric headache treatment?

Headache: The Journal of Head and Face Pain, EarlyView.
Amy A. Gelfand, Christina L. Szperka
wiley   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

Developmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón, Nuria Carreras, Tobias Muehlbacher, Dídac Casas‐Alba, Roberta Arena, Paola Roca‐Llabrés, Juan Navarro‐Morón, Linda S. de Vries, Paul Govaert, the EurUS.Brain group, Thais Agut, Roberta Arena, Ana Alarcón, Juan Arnáez, Marco Bartocci, Isabel Benavente‐Fernández, María Carmen Bravo, Fernando Cabañas, Nuria Carreras, Olivier Claris, Jeroen Dudink, Monica Fumagalli, Alfredo García‐Alix, Paul Govaert, Sandra Horsch, Simón Lubián, Tobias Muehlbacher, Alessandro Parodi, Adelina Pellicer, Luca Ramenghi, Charles C. Roehr, Simone Schwarz, Sylke Steggerda, Eva Valverde   +33 more
wiley   +1 more source

Topical timolol for small infantile hemangioma: a new therapy option

The Turkish Journal of Pediatrics, 2012
The main characteristic of infantile hemangioma is that it grows rapidly after birth and mostly regresses spontaneously. It is a common practice for only a small part of the hemangioma to be treated, as they can be extremely disfiguring and ...
Anne Weissenstein, Alexandra Straeter, Gloria Villalon, Stefan Bittmann   +3 more
doaj  

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

eLife, 2019
Propranolol is an approved non-selective β-adrenergic blocker that is first line therapy for infantile hemangioma. Despite the clinical benefit of propranolol therapy in hemangioma, the mechanistic understanding of what drives this outcome is limited ...
Jeroen Overman, Frank Fontaine, Jill Wylie-Sears, Mehdi Moustaqil, Lan Huang, Marie Meurer, Ivy Kim Chiang, Emmanuelle Lesieur, Jatin Patel, Johannes Zuegg, Eddy Pasquier, Emma Sierecki, Yann Gambin, Mohamed Hamdan, Kiarash Khosrotehrani, Gregor Andelfinger, Joyce Bischoff, Mathias Francois   +17 more
doaj   +1 more source

Sirolimus in the Management of Complex Infantile Hemangiomas: A State‐of‐the‐Art Review

Pediatric Dermatology, Volume 42, Issue 6, Page 1126-1132, November/December 2025.
ABSTRACT Infantile hemangiomas (IHs) are common, benign vascular tumors frequently managed with beta‐blockers as first‐line therapy. While most IHs respond to propranolol, a subset of severe, refractory, or life‐threatening lesions requires alternative interventions.
Fabiana C. P. S. Lopes, Moise L. Levy, Jennifer S. Ruth, Ginna Priola, Shoshana Greenberger   +4 more
wiley   +1 more source

Propranolol Treatment in the Management of Infantile Hemangioma in Erbil, Iraq [PDF]

Iranian Journal of Neonatology
Background: Infantile hemangioma is a common benign vascular tumor that affects up to 10% of infants. Propranolol, a beta-blocker, has been used as a promising treatment for infantile hemangioma, but its effectiveness remains controversial.
Wesam Boya Kaka, Siamand Salim, Jalal Fattah   +2 more
doaj   +1 more source

Treatment With Propranolol for Infantile Hemangioma in 13 Taiwanese Newborns and Young Infants

Pediatrics and Neonatology, 2012
Hemangioma in infants has a benign self-limited course, but the 10% of cases with complications need further treatment. Successful treatment with propranolol in western countries has been reported over the past few years.
Teng-Chin Hsu, Jiaan-Der Wang, Chao-Huei Chen, Te-Kau Chang, Teh-Ming Wang, Chia-Man Chou, Heng-Kuei Lin   +6 more
doaj   +1 more source

Experience with the successful use of topical beta-adrenoblockers in the treatment of infantile hemangiomas: a clinical case and review of the literature

Лечащий Врач
Background. Infantile (infantile) hemangiomas are benign vascular tumors found predominantly in the pediatric population. Its presence can lead not only to aesthetic discomfort of the child, but also to gross functional disorders.
R. V. Saranyuk, T. A. Gosteva
doaj   +1 more source