Results 111 to 120 of about 59,645 (241)
The multiple hit model of infantile and epileptic spasms: The 2025 update
Epilepsia Open, EarlyView.Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Clinical profile of vigabatrin as monotherapy for treatment of infantile spasms
Neuropsychiatric Disease and Treatment, 2010 Jason T Lerner1, Noriko Salamon2, Raman Sankar1,31Departments of Pediatrics, 2Radiological Sciences, 3Neurology, David Geffen School of Medicine, University of California Los Angeles and Mattel Children’s Hospital at UCLA, Los Angeles, CA ...
Jason T Lerner +2 more
doaj
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Adapting Action Recognition Neural Networks for Automated Infantile Spasm Detection
IEEE Transactions on Neural Systems and Rehabilitation EngineeringInfantile spasms are a severe epileptic syndrome characterized by short muscular contractions lasting from 0.5 to 2 seconds. They are often misdiagnosed due to their atypical presentation, and treatment is frequently delayed, leading to stagnation or ...
Samuel Diop +4 more
doaj +1 more source
Utility of repeat stereotactic EEG in pediatric patients with tuberous sclerosis
Epilepsia Open, EarlyView.Abstract Objective Tuberous sclerosis complex (TSC) is a rare genetic disorder associated with early‐onset drug‐resistant epilepsy (DRE) secondary to intracranial tubers. Many patients undergo stereo‐EEG (sEEG) for seizure onset localization, sometimes requiring multiple sEEGs and subsequent epilepsy surgeries. Our objective was to evaluate the effects
Julie Uchitel +14 more
wiley +1 more source
The ACTH Quandary: Balancing Efficacy and Affordability for Infantile Spasms Treatment. [PDF]
Epilepsy Curr, 2023 Aungaroon G.
europepmc +1 more source
Affective Disorders in Infantile Spasms
, 1999 Facial expression of affect in 28 children with intractable infantile spasms was studied longitudinally for 1.8 years after epilepsy surgery, at the Department of Psychiatry, Mental Retardation Research Center, UCLA, Los ...
J Gordon Millichap, J Gordon Millichap
core +1 more source
Epilepsia Open, EarlyView.Abstract Objective Epileptic spasms (ES) in children carry a high risk of neurodevelopmental delay, yet predictors of long‐term surgical outcome remain incompletely defined. This study aimed to evaluate seizure outcomes following epilepsy surgery and to identify independent prognostic factors for postoperative recurrence.
Hua Li +7 more
wiley +1 more source
A case of infantile spasms with three possibly pathogenic de novo missense variants in NF1 and GABBR1. [PDF]
Hum Genome Var, 2023 Watanabe K +3 more
europepmc +1 more source
CSF Tryptophan in Infantile Spasms
, 1992 The levels of tryptophan (TRP) metabolites in the CSF of 8 patients with infantile spasms are reported from the Department of Pediatrics, St.
J Gordon Millichap
core +1 more source