Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]
Frontiers in PediatricsIntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Hao Ding, Baomin Li, Li Baomin
exaly +7 more sources
Different pharmacoresistance of focal epileptic spasms, generalized epileptic spasms, and generalized epileptic spasms combined with focal seizures [PDF]
Epilepsia Open, 2022 Objective Among standard treatments for infantile spasms, adrenocorticotropic hormone (ACTH) is reported as the best treatment, but ACTH is ineffective in one‐half of the patients.
Yukitoshi Takahashi, Takushi Inoue
exaly +4 more sources
Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience [PDF]
EpilepsiaAbstractObjectiveLead time to treatment (clinical onset of epileptic spasms [ES] to initiation of appropriate treatment) is known to predict outcomes in infantile epileptic spasms syndrome (IESS). Timing the clinical onset of ES is crucial to establish lead time. We investigated how often ES onset could be established to the nearest week.
Aristides Hadjinicolaou +2 more
exaly +5 more sources
Infantile epileptic spasms syndrome: Mechanisms and therapeutic approaches [PDF]
NeurotherapeuticsInfantile epileptic spasms syndrome (IESS) is a developmental and. epileptic encephalopathy with unique clinical and electrographic features, including seizure semiology (spasms), numerous and diverse etiologies spanning structural, genetic and metabolic
Carl E. Stafstrom
doaj +3 more sources
Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]
Frontiers in PediatricsBackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen +13 more
doaj +3 more sources
Electroclinical Features of Infantile Epileptic Spasms Syndrome [PDF]
Annals of Indian Academy of NeurologyEpileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
doaj +4 more sources
EBioMedicine, 2022 Summary: Background: Epileptic (previously infantile) spasms is the most common epileptic encephalopathy occurring during infancy and is frequently associated with abnormal neurodevelopmental outcomes.
Erica Tsang +2 more
exaly +3 more sources
Status Epilepticus Manifested as Continuous Epileptic Spasms [PDF]
Frontiers in Neurology, 2020 Objective: The etiology and outcome of status epilepticus with continuous epileptic spasms have not been fully understood; and only rare cases have been reported in the literature.
Jianxiang Liao +12 more
doaj +3 more sources
IESS-FusionNet: Physiologically Inspired EEG-EMG Fusion with Linear Recurrent Attention for Infantile Epileptic Spasms Syndrome Detection [PDF]
BioengineeringInfantile Epileptic Spasms Syndrome (IESS) is a devastating epileptic encephalopathy of infancy that carries a high risk of lifelong neurodevelopmental disability.
Junyuan Feng +6 more
doaj +2 more sources
Frontiers in Neurology, 2023 ObjectiveEpileptic spasms are a type of seizure defined as a sudden flexion or extension predominantly of axial and/or truncal limb muscles that occur with a noticeable periodicity. Routine electroencephalogram supports the diagnosis of epileptic spasms,
Raffaele Falsaperla +8 more
doaj +1 more source