Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome [PDF]
Frontiers in PediatricsIntroductionInfantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China.
Baomin Li
exaly +6 more sources
Different pharmacoresistance of focal epileptic spasms, generalized epileptic spasms, and generalized epileptic spasms combined with focal seizures [PDF]
Epilepsia Open, 2022 Objective Among standard treatments for infantile spasms, adrenocorticotropic hormone (ACTH) is reported as the best treatment, but ACTH is ineffective in one‐half of the patients.
Jun Tohyama +2 more
exaly +4 more sources
EBioMedicine, 2022 Summary: Background: Epileptic (previously infantile) spasms is the most common epileptic encephalopathy occurring during infancy and is frequently associated with abnormal neurodevelopmental outcomes.
Russell C Dale +2 more
exaly +3 more sources
Status Epilepticus Manifested as Continuous Epileptic Spasms [PDF]
Frontiers in Neurology, 2020 Objective: The etiology and outcome of status epilepticus with continuous epileptic spasms have not been fully understood; and only rare cases have been reported in the literature.
Jianxiang Liao +12 more
doaj +3 more sources
Epileptic spasms in the acute phase of pediatric anti-N-methyl-d-aspartate receptor encephalitis: a case series [PDF]
Frontiers in ImmunologyBackgroundAnti-N-methyl-D-aspartate receptor encephalitis (NMDARE) is an autoimmune disorder characterized by a broad spectrum of neuropsychiatric symptoms.
Pingping Tian +5 more
doaj +2 more sources
Ketogenic diet for infantile epileptic spasms. [PDF]
Epilepsia OpenAbstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS.
Scantlebury MH +3 more
europepmc +3 more sources
Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome [PDF]
Epilepsia OpenObjective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (
Thomas Harman +5 more
doaj +2 more sources
Electroclinical Features of Infantile Epileptic Spasms Syndrome
Annals of Indian Academy of NeurologyEpileptic spasms are a unique, age-dependent manifestation of epilepsies in infancy and early childhood, commonly occurring as part of infantile epileptic spasms syndrome.
Gozde Erdemir, Ahsan N. Moosa
doaj +3 more sources
Infantile epileptic spasms syndrome: Mechanisms and therapeutic approaches [PDF]
NeurotherapeuticsInfantile epileptic spasms syndrome (IESS) is a developmental and. epileptic encephalopathy with unique clinical and electrographic features, including seizure semiology (spasms), numerous and diverse etiologies spanning structural, genetic and metabolic
Carl E. Stafstrom
doaj +2 more sources
Smartphone videos for infantile epileptic spasms triaging and assessment (VISTA study): Impact of education and standardized clinical history on diagnostic accuracy [PDF]
Epilepsia OpenObjective Diagnostic and treatment delays in infantile epileptic spasms syndrome (IESS) increase the risk of poor neurodevelopmental outcomes.
Christine L. Shrock +11 more
doaj +2 more sources