Results 141 to 150 of about 17,755 (294)

EEG functional connectivity as a marker of evolution from infantile epileptic spasms syndrome to Lennox–Gastaut syndrome

Epilepsia, EarlyView.
Abstract Objective Timely diagnosis and effective treatment of Lennox–Gastaut syndrome (LGS) improve prognosis and lower health care costs, but the transition from infantile epileptic spasms syndrome (IESS) to LGS is highly variable and insidious. Objective biomarkers are needed to monitor this progression and guide clinical decision‐making. Methods We
Blanca Romero Milà, Virginia B. Liu, Rachel J. Smith, Derek K. Hu, Natalie A. Benneian, Shaun A. Hussain, Maija Steenari, Donald Phillips, David Adams, Clare Skora, Beth A. Lopour, Daniel W. Shrey   +11 more
wiley   +1 more source

Cognitive deficits after cryptogenic infantile spasms with benign seizure evolution [PDF]

, 1999
Eija Gaily, Kati Appelqvist, Elisa Kantola‐Sorsa, Elina Liukkonen, Paula Kyyrönen, Mia Sarpola, Heli Huttunen, Leena Valanne, Marja‐Liisa Granström   +8 more
openalex   +1 more source

Cortical Parvalbumin-positive Interneuron Development and Function are Altered in the APC Conditional Knockout Mouse Model of Infantile Spasm Syndrome [PDF]

, 2022
Rachael F. Ryner, Isabel D. Derera, Moritz Armbruster, Anar Kansara, Mary Sommer, Antonella Pirone, Farzad Noubary, Michele H. Jacob, Chris G. Dulla   +8 more
openalex   +1 more source

Pediatric Investigation Plans for seizure and epilepsy treatments: An analysis since the implementation of the European Pediatric Regulation in 2006

Epilepsia, EarlyView.
Abstract Objective A Pediatric Investigation Plan (PIP) implemented under the European Pediatric Regulation (EC No. 1901/2006) aims to ensure early and systematic evaluation of medicines for children. We analyze PIPs for antiseizure medications (ASMs) submitted to the European Medicines Agency (EMA) since 2006, characterizing their content, focusing on
Valeria Agostini, Stéphane Auvin
wiley   +1 more source

More Hormones, Less Spasms: IGF-1 as a Potential Therapy for Infantile Spasms. [PDF]

Epilepsy Curr, 2023
Dang LT.
europepmc   +1 more source

Treatment of infantile spasms with very high dose prednisolone before high dose adrenocorticotropic hormone

, 2013
Shaun A. Hussain, Shlomo Shinnar, Grace Kwong, Jason T. Lerner, Joyce H. Matsumoto, Joyce Y. Wu, W. Donald Shields, Raman Sankar   +7 more
openalex   +1 more source

Vigabatrin therapy for infantile spasms: review of major trials in Europe, Canada, and the United States; and recommendations for dosing [PDF]

, 2011
Lionel Carmant
openalex   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

Epilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon, Jan H. Magielski, Bintou Bane, JoeyLynn Nolan, Sarah M. Ruggiero, Dallas Armstrong, Susan Arnold, Deepa Sirsi, Ingo Helbig, Jillian L. McKee   +9 more
wiley   +1 more source

Response to treatment and outcomes of infantile spasms in Down syndrome. [PDF]

Dev Med Child Neurol, 2022
Harvey S, Allen NM, King MD, Lynch B, Lynch SA, O'Regan M, O'Rourke D, Shahwan A, Webb D, Gorman KM, Irish Paediatric Neurology Group.   +10 more
europepmc   +1 more source

Recent Advances in the Pharmacotherapy of Infantile Spasms [PDF]

, 2014
Raili Riikonen
openalex   +1 more source