Results 21 to 30 of about 59,645 (241)

Impact of vigabatrin on risk of relapse of infantile spasms. [PDF]

Epilepsia Open
Abstract Objective Vigabatrin is an effective treatment for infantile epileptic spasms syndrome (IESS), but relapse remains a clinical challenge. The ideal dose and duration of treatment after response are unknown. We set out to identify treatment‐related predictors of IESS relapse after initial vigabatrin response. Methods We conducted a retrospective
Carmenate YI, Ahn HE, Peters HR, Nariai H, Rajaraman RR, Hussain SA.   +5 more
europepmc   +2 more sources

Case Report: Rituximab Improved Epileptic Spasms and EEG Abnormalities in an Infant With West Syndrome and Anti-NMDAR Encephalitis Associated With APECED

Frontiers in Neurology, 2021
Background: Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is a rare autosomal recessive disorder caused by a mutation in the autoimmune regulator gene.
Go Kawano, Takaoki Yokochi, Ryuta Nishikomori, Yoriko Watanabe, Keizo Ohbu, Yukitoshi Takahashi, Haruo Shintaku, Toyojiro Matsuishi, Toyojiro Matsuishi, Toyojiro Matsuishi   +9 more
doaj   +1 more source

Treatment of Infantile Spasms [PDF]

, 2011
Infantile spasms is an epileptic encephalopathy of early infancy with specific clinical and electroencephalographic (EEG) features, limited treatment options, and a poor prognosis.
Anna Catania, Tallie Z. Baram, Raili Riikonen, Tracy A. Glauser, Rogawski, Michael A, Pranzatelli, Michael R, Miguel A. Cortez, Baram, Tallie Z, Swann, John W, Catania, Anna, Michael R. Pranzatelli, Carl E. Stafstrom, Barry G. W. Arnason, Stafstrom, Carl E, Glauser, Tracy A, Shlomo Shinnar, Arnason, Barry GW, Michael A. Rogawski, Cortez, Miguel A, Riikonen, Raili, Shinnar, Shlomo, John W. Swann   +21 more
core   +1 more source

Aicardi Syndrome: A Rare Cause of Infantile Spasms [PDF]

International Journal of Anatomy Radiology and Surgery
Infantile spasms may occur in isolation or as part of multiple neurodevelopmental syndromes. We report an eight-month-old female infant presenting with infantile spasms, developmental delay, and characteristic features of Aicardi syndrome ...
Rituparna Das, Amolpreet Kumar Saini, Namdev Seth   +2 more
doaj   +1 more source

The Epidemiology of Infantile Spasms [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2001
Objective:The aim of this study was to estimate population based incidence rates for infantile spasms (IS) and to study our clinical impression that the incidence of IS has recently decreased in the Canadian Provinces of Nova Scotia and Prince Edward Island.Methods:Birth cohorts from 1978 to 1998, identified through the hospital health records, EEG ...
P M, Brna, K E, Gordon, J M, Dooley, E P, Wood   +3 more
openaire   +2 more sources

Investigations in West Syndrome: Which, When and Why

Pediatric Neurology Briefs, 2015
Investigators from the National Infantile Spasms Consortium (NISC) in the USA studied the etiology of new-onset infantile spasms (IS) in 251 infants (mean age at onset, 7.1, range, 0.1-22.7 months).
Richard E Appleton
doaj   +1 more source

Historical Patterns of Diagnosis, Treatments, and Outcome of Epilepsy Associated With Tuberous Sclerosis Complex: Results From TOSCA Registry

Frontiers in Neurology, 2021
Background: Epilepsy is the most common neurological manifestation in individuals with tuberous sclerosis complex (TSC). However, real-world evidence on diagnosis and treatment patterns is limited.
Rima Nabbout, Elena Belousova, Mirjana P. Benedik, Tom Carter, Vincent Cottin, Paolo Curatolo, Maria Dahlin, Lisa D'Amato, Guillaume Beaure d'Augères, Petrus J. de Vries, José C. Ferreira, Martha Feucht, Carla Fladrowski, Carla Fladrowski, Christoph Hertzberg, Sergiusz Jozwiak, Sergiusz Jozwiak, John A. Lawson, Alfons Macaya, Ruben Marques, Ruben Marques, Finbar O'Callaghan, Jiong Qin, Matthias Sauter, Seema Shah, Yukitoshi Takahashi, Renaud Touraine, Sotiris Youroukos, Bernard Zonnenberg, Anna C. Jansen, J. Chris Kingswood   +30 more
doaj   +1 more source

Safety and Efficacy of Vigabatrin for the Treatment of Infantile Spasms

Journal of Central Nervous System Disease, 2011
In 2009, vigabatrin became the first FDA approved medication for the treatment of infantile spasms in the United States. There are few well-designed prospective studies comparing the drug to placebo or other modalities used in the treatment of infantile ...
Michele A. Faulkner, Justin A. Tolman
doaj   +1 more source

Vigabatrin therapy implicates neocortical high frequency oscillations in an animal model of infantile spasms

Neurobiology of Disease, 2015
Abnormal high frequency oscillations (HFOs) in EEG recordings are thought to be reflections of mechanisms responsible for focal seizure generation in the temporal lobe and neocortex. HFOs have also been recorded in patients and animal models of infantile
James D. Frost, Jr., John T. Le, Chong L. Lee, Carlos Ballester-Rosado, Richard A. Hrachovy, John W. Swann   +5 more
doaj   +1 more source

Infantile Spasms Treated with Intravenous Methypredinsolone Pulse [PDF]

, 2017
How to Cite This Article: Hassanzadeh Rad A, Aminzadeh V. Infantile Spasms Treated with Intravenous Methypredinsolone Pulse. Iran J Child Neurol. Spring 2017; 11(2):8-12.AbstractObjectiveInfantile spasms is diagnosed late even by expert pediatricians ...
HASSANZADEH RAD, Afagh, AMINZADEH, vahid
core   +1 more source