Results 21 to 30 of about 9,877 (241)
Current Treatment Options in Neurology, 2006 Infantile spasms (IS) are characterised by neurodevelopmental regression, a unique type of seizures and a hypsarrhythmic EEG pattern. Studies recommend the medical treatment of IS as a positive short-term outcome with respect to the spasms and in the ...
Kjærsgård, Lars, Rasmussen, Niels
core +4 more sources
Pediatric Neurology, 1990 The rationale, dosage, and side effects of ACTH treatment of infantile spasms are reviewed from the Department of Neurology, University of Southern California School of Medicine, and Children’s Hospital of Los Angeles ...
J Gordon Millichap
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Pathophysiology of Infantile Spasms
Pediatric Neurology Briefs, 1993 An age-specific endogenous-convulsant hypothesis implicating corticotropin-releasing hormone (CRH), an excitant neuropeptide suppressed by ACTH/steroids, is proposed for the pathophysiology of massive infantile spasms in a report from the University of ...
J Gordon Millichap
doaj +3 more sources
Pediatric Neurology Briefs, 1993 The developmental, neurologic, and seizure outcome and prognostic factors of 57 cases of infantile spasms were evaluated in relation to etiology (cryptogenic 17 cases, symptomatic 40 cases) at the Hospital for Sick Children, Toronto, Canada.
J Gordon Millichap
doaj +2 more sources
Pediatric Neurology Briefs, 2001 Early electroclinical manifestations and treatment responses were evaluated by video-EEG in 44 infants with infantile spasms.
J Gordon Millichap
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Pediatric Neurology Briefs, 1990 The relationship between dose of ACTH and the initial effect and long-term prognosis was investigated in 41 children with infantile spasms at the Department of Pediatrics, Kyoto University, Kyoto, Japan.
J Gordon Millichap
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Seizure Outcome in Infantile Spasms
Pediatric Neurology Briefs, 2011 Researchers at Great Ormond Street Hospital, London, and Lingfield Centre for Epilepsy, Surrey, UK, studied retrospectively the seizure outcome of 75 children treated over an 8-year period for infantile spasms (IS) with prednisolone or vigabatrin.
J Gordon Millichap
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
wiley +1 more source
Seizure Prediction Analysis of Infantile Spasms
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023 Infantile spasms (IS) is a typical childhood epileptic disorder with generalized seizures. The sudden, frequent and complex characteristics of infantile spasms are the main causes of sudden death, severe comorbidities and other adverse consequences ...
Runze Zheng +5 more
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Pediatric Clinics of North America, 1989 Infantile spasms are a unique disorder of infancy and early childhood. The average age at onset of infantile spasms is 6 months and the average incidence of the disorder is approximately 0.31 per 1000 live births. Approximately one-quarter of patients will spontaneously stop having spasms within 1 year of onset.
R A, Hrachovy, J D, Frost
openaire +6 more sources