Results 221 to 230 of about 1,818,543 (386)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

The mediating role of blood metabolites in the association between myocardial infarction and cancer risk: An observational and mendelian randomization analysis. [PDF]

PLoS One
Zhu J, Xia X, Jiang H, Wang C, Jin Y.
europepmc   +1 more source

The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.

Circulation Research, 2016
S. Prabhu, N. Frangogiannis
semanticscholar   +1 more source

Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

Nature Biomedical Engineering, 2020
D. Richards, D. Richards, Yang Li, Charles M. Kerr, Jenny Yao, Jenny Yao, G. Beeson, Robert C. Coyle, Xun Chen, Jia Jia, B. Damon, Robert C. Wilson, E. Hazard, G. Hardiman, G. Hardiman, D. Menick, C. Beeson, Hai Yao, Tong Ye, Ying Mei, Ying Mei   +20 more
semanticscholar   +1 more source

Piezo1 Upregulation in Monocyte‐Derived Macrophages Impairs Post‐Myocardial Infarction Cardiac Repair via Defective Efferocytosis and Enhanced Ferroptosis

Advanced Science, EarlyView.
This study reports early Piezo1 activation in bone marrow monocyte‐derived macrophages (MoMs) during myocardial infarction (MI), which governs the fate and function of recruited macrophages. The recruited MoMs with increased Piezo1 expression exhibit increased ferroptosis and defective efferocytosis, delayed clearance of dead cells and resolution of ...
Lu Peng, Yunlong Xia, Huishou Zhao, Yongzhen Guo, Xiaoming Xu, Xue Han, Shiyue Wang, Fengyue Ding, Quanchi Liu, Congye Li, Yuan He, Zhaoyi Luo, Qiaojuan Wang, Xing Zhang, Feng Gao, Yajing Wang, Yulin Li, Shengpeng Wang, Ling Tao, Wenjun Yan   +19 more
wiley   +1 more source

Secondary cardiocerebral infarction after acute inferior myocardial infarction treated with two emergency thrombectomies: a case report. [PDF]

Front Med (Lausanne)
Dong MZ, Zhu EB, Lin MQ, Dong GH, Jin GL, Qu LZ, Che HY, Guan HJ.   +7 more
europepmc   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Seizure recurrence after first epileptic episode in ischemic stroke: Risk factors and their association with cognition and mood. [PDF]

World J Psychiatry
Wang SY, Zhang DD, Li NN.
europepmc   +1 more source

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Pre-PCI SGLT2 inhibitors and contrast-induced nephropathy in acute myocardial infarction: A meta-analysis. [PDF]

Medicine (Baltimore)
Li Y, Zhang W, Li R.
europepmc   +1 more source