Results 161 to 170 of about 22,674 (264)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, Volume 16, Issue 4, Page 737-750, April 2026.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Fatal Spontaneous Retroperitoneal Hematoma Following Intense Physical Exertion in a Young Healthy Male: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT In young adults who experience sudden flank or abdominal pain and hemodynamic instability following intense physical activity, spontaneous retroperitoneal hemorrhage due to an iliac arterial lesion must be considered, even in the absence of evident contrast extravasation on CT angiography, requiring immediate endovascular assessment and damage‐
Golnaz Moradi, Pezhman Farshidmehr, Reyhane Yahya, Hoda Asefi, Samira Mirzaei   +4 more
wiley   +1 more source

Acute Invasive Pulmonary Aspergillosis With CNS Dissemination in an Immunocompetent Individual: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Invasive pulmonary aspergillosis can occur in patients without classical immunosuppression, particularly those with COPD and corticosteroid exposure. Early recognition, prompt antifungal therapy, and vigilance for neurological symptoms are essential to prevent central nervous system dissemination, which carries high mortality and significant ...
Barbare Khatiashvili, Sarah Saife, Islam Rajab, Malina Mohtadi, Arham Hazari, Ghassan Makhoul, Aqsa Zoey Sorathia, Ahmad Huzien, Shivanck Upadhyay   +8 more
wiley   +1 more source

Low‐Intensity Pulsed Ultrasound Promotes Spinal Cord Injury Recovery by Regulating Microglia‐Mediated Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Low‐intensity pulsed ultrasound (LIPUS) exerts a neuroprotective effect in spinal cord injury (SCI) by regulating microglial polarization: it inhibits pro‐inflammatory M1 phenotype activation, promotes anti‐inflammatory M2 phenotype polarization, alleviates neuroinflammation, inhibits neuronal apoptosis, reduces spinal cord cavity formation, and ...
Xiaoyu Li, Yang Liu, Wanghui Liu, Tian Wang, Hanfei Shang, Hongji Zhong, Zixiang Deng, Xiaoyi Zhou, XianZhao Wei   +8 more
wiley   +1 more source

A Case of Perforated Peritonitis Caused by the Migration of a Single‐Puncture Gastric Wall Fixation Device Following Percutaneous Endoscopic Gastrostomy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract We report an uncommon case of perforated peritonitis resulting from the migration of a single‐puncture gastric wall fixation device following percutaneous endoscopic gastrostomy. An 83‐year‐old male developed acute peritonitis 6 days post‐procedure, requiring emergency surgery.
Yuu Kodama, Yuji Mizokami, Hidemitsu Nishizawa, Gen Maeda, Gen Kimura, Yuzo Toyama, Shingo Asahara, Ryuji Nagahama, Hideki Sunagawa   +8 more
wiley   +1 more source

Secondary Aortoduodenal Fistula Diagnosed after Repeated Gastrointestinal Bleeding Episodes in a Patient With Prior Aortic Graft Surgery

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Secondary aortoduodenal fistula (sADF) is a rare but life‐threatening complication after aortic graft surgery. Diagnosis is often challenging, particularly when contrast‐enhanced computed tomography (CT) and endoscopy results are inconclusive. We report a case in which diagnosis was challenging due to contrast media allergy and non‐diagnostic ...
Jun Kubota, Chikamasa Ichita, Soichiro Nakaya, Takashi Nishino, Chihiro Sumida, Akiko Sasaki, Daisuke Hama   +6 more
wiley   +1 more source

Endoscopic Step‐up Approach for Walled‐off Necrosis After Acute Pancreatitis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Shuntaro Mukai, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Yukitoshi Matsunami, Kazumasa Nagai, Hiroyuki Kojima, Hirohito Minami, Noriyuki Hirakawa, Kyoko Asano, Kento Shionoya, Kazuki Hama, Takao Itoi   +13 more
wiley   +1 more source

Infected aneurysm after returning from Southeast Asia: think Burkholderia pseudomallei! [PDF]

BMJ Case Rep, 2019
Auvens C, Neuwirth C, Piroth L, Blot M.
europepmc   +1 more source

Endoscopic Closure Combined With the Endoscopic Submucosal Dissection Technique and Over‐the‐scope Clip for Chronic Aortoesophageal Fistula: A Case Report

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Aortoesophageal fistula (AEF) is a rare but life‐threatening condition. Initial management typically includes thoracic endovascular aortic repair (TEVAR) or aortic graft replacement to achieve hemostasis, followed by esophagectomy with aortic graft replacement and greater omentum wrapping to eliminate the source of infection.
Ryosuke Kawagoe, Toshiaki Narasaka, Takashi Mamiya, Masaaki Nishi, Kiichiro Tsuchiya   +4 more
wiley   +1 more source

Successful endovascular repair of a chronic Q fever-associated abdominal aortic infected aneurysm. [PDF]

J Vasc Surg Cases Innov Tech
Huang JX, Kwan KJS, Tam SC, Li HL, Cui DZ, Cheng SWK.   +5 more
europepmc   +1 more source