Results 151 to 160 of about 1,184,326 (242)

Antibiotic therapy for prophylaxis against infection of pancreatic necrosis in acute pancreatitis

, 2010
Background Pancreatic necrosis may complicate severe acute pancreatitis, and is detectable by computed tomography (CT). If it becomes infected mortality increases, but the use of prophylactic antibiotics raises concerns about antibiotic resistance and ...
E. Villatoro (12595615), M. Mulla (12595618), MICHAEL LARVIN (12349672)   +2 more
core  

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Approach to the Diagnosis and Management of Infected Pancreatic Necrosis: A Narrative Review. [PDF]

Cureus
Sahu SK, Giri S, Das S, Patro CD, Praharaj DL, Mallick B, Nath P, Panigrahi SC, Anand AC.   +8 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

A Nomogram for Early Prediction of Infected Pancreatic Necrosis Based on Contrast-Enhanced CT Radiomics and Inflammatory Indicators. [PDF]

J Inflamm Res
Yao Q, Duan Y, Jin C, Li X, Wei S, Shi Y, Zhang Y, Zhang J, Liu C.   +8 more
europepmc   +1 more source

Infected pancreatic necrosis complicating severe acute pancreatitis in critically ill patients: predicting catheter drainage failure and need for necrosectomy. [PDF]

Ann Intensive Care, 2022
Garret C, Douillard M, David A, Péré M, Quenehervé L, Legros L, Archambeaud I, Douane F, Lerhun M, Regenet N, Gournay J, Coron E, Frampas E, Reignier J.   +13 more
europepmc   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Case Report: Early documented infected pancreatic necrosis due to carbapenem-resistant <i>Acinetobacter baumannii</i> and concurrent <i>Enterococcus faecium</i> bacteremia: a salvage regimen with sulbactam-durlobactam and tigecycline. [PDF]

Front Med (Lausanne)
Li M, Fu Y, Chen Y, Yu Y.
europepmc   +1 more source

Plasma metagenomic next-generation sequencing of microbial cell-free DNA detects pathogens in patients with suspected infected pancreatic necrosis. [PDF]

BMC Infect Dis, 2022
Hong D, Wang P, Zhang J, Li K, Ye B, Li G, Zhou J, Tong Z, Ke L, Shi S, Li W.   +10 more
europepmc   +1 more source