Results 141 to 150 of about 49,177 (304)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Course of pancreatic necrosis on a background of major duodenal papilla stone

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. To estimate course of biliary pancreatic necrosis (PN) on a background of an «impacted» stone of major duodenal papilla in comparison to pancreatic necrosis of alimentary origin.Material and methods. Treatment results of 76 patients
S. V. Mikhaylusov, Ye. V. Moiseyenkova, M. M. Misrokov   +2 more
doaj  

The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis

British Journal of Pharmacology, EarlyView.
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan, Karen Hon, Ruby E. Dawson, Teresa Weng, Jelena Solujic, Yu C. J. Chey, James D. Zuiani, Griffith B. Perkins, P. Toby Coates, Chris Drogemuller, Eddie Sanderlin, Lulu Huang, John Finnie, Stefan Rose‐John, Arash Badiei, Phan Nguyen, Brendan J. Jenkins, Mohamed I. Saad   +17 more
wiley   +1 more source

Central blood volume in cirrhosis [PDF]

, 1993
Bendtsen, Flemming, Gerbes, Alexander L., Henriksen, Jens H.   +2 more
core   +1 more source

Contrast-enhanced computed tomography in acute pancreatitis: does contrast medium worsen its course due to impaired microcirculation? [PDF]

, 2018
Background: An early and accurate diagnosis of severe acute (necrotizing) pancreatitis is important to allow timely institution of therapy to limit the extra-pancreatic sequelae of this necrotizing process and to minimize the incidence of super-infection
Anderson, Suzanne, Plock, Jan, Roggo, Antoine, Sarr, Michael, Schmidt, Joachim   +4 more
core  

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Risk Factors and Outcomes of Multidrug-Resistant Bacteria Infection in Infected Pancreatic Necrosis Patients. [PDF]

Infect Drug Resist, 2022
Lu J, Ding Y, Qu Y, Mei W, Guo Y, Fang Z, Qu C, Gao C, Cao F, Li F, Feng Y.   +10 more
europepmc   +1 more source

Эффективность иммобилизированной формы гипохлорита натрия в лечении экспериментального инфицированного панкреонекроза [PDF]

, 2016
ПОДЖЕЛУДОЧНАЯ ЖЕЛЕЗА /патологинфицированный панкреонекроз /лек тергнойные воспаленияСАЛЬНИКНАТРИЯ ГИПОХЛОРИТ /приемМАЗИ /тер примЭКСПЕРИМЕНТЫ НА ЖИВОТНЫХЛЕЧЕНИЯ РЕЗУЛЬТАТОВ ОЦЕНКАЦель.
Артюшкова, Е. Б., Еленская, Е. А., Итинсон, А. А., Итинсон, А. И., Суковатых, Б. С.   +4 more
core  

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin, Hui‐Fang Chang, Tzu‐Ching Lin, Cheng‐Han Lin, Yu‐Ling Sun, Chih‐Sheng Lin   +5 more
wiley   +1 more source

Evaluating the role of the Minimal Incision Retroperitoneal Necrosectomy (MIRN) in the management of infected pancreatic necrosis: Experience from a tertiary care center. [PDF]

Surg Open Sci, 2023
Avudiappan M, Bhargava V, Kulkarni A, Kang M, Rana SS, Gupta R.   +5 more
europepmc   +1 more source