Results 121 to 130 of about 1,184,326 (242)

Infected pancreatic necrosis and peripancreatic fluid collections: Serendipitous response to antibiotics and medical therapy in three patients

open access: yes, 1996
Three patients with clinical and radiologic evidence of pancreatic necrosis or peripancreatic fluid collections/inflammatory masses who were advised to have surgery on the basis of bacterial infection on skinny-needle aspiration of the pancreas but were ...
H. Dubner   +5 more
core   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang   +2 more
wiley   +1 more source

Factors Contributing to Improved Bone Mineral Density in Patients With Transfusion‐Dependent Thalassemia

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Advances in therapy have extended the life expectancy of patients with thalassemia to near that of the general population; complications such as endocrine disorders and osteoporosis remain prevalent. This study aimed to identify endocrine complications, factors associated with endocrine complications, and changes in bone mineral density (BMD ...
Cheng‐Ying Hsu   +7 more
wiley   +1 more source

Course of pancreatic necrosis on a background of major duodenal papilla stone

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. To estimate course of biliary pancreatic necrosis (PN) on a background of an «impacted» stone of major duodenal papilla in comparison to pancreatic necrosis of alimentary origin.Material and methods. Treatment results of 76 patients
S. V. Mikhaylusov   +2 more
doaj  

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers   +5 more
wiley   +1 more source

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

open access: yesThe Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li   +6 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

ANTIBACTERIAL THERAPY OF INFECTED PANCREATIC NECROSIS IN A MULTIFIELD SURGICAL HOSPITAL [PDF]

open access: yes, 2012
The work is based, on the analysis of the results of complex conservative and surgical treatment of 50 patients with infected, forms of pancreatic necrosis, who were treated in surgical wards of Republican, hospital № 2 — Center of Emergency Medical Care
N. M. Gogolev   +4 more
core  

Expert consensus on clinical trial design guidelines for FLASH radiotherapy

open access: yesPrecision Radiation Oncology, EarlyView.
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo   +9 more
wiley   +1 more source

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

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