Results 101 to 110 of about 24,001 (251)

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

Stump Ischemia Is a Possible Risk Factor for Late‐Onset Pancreatic Fistula After Distal Pancreatectomy

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background This study was conducted to determine the clinical significance of pancreatic stump ischemia (PSI) in predicting late‐onset pancreatic fistula (LOPF) following stapled distal pancreatectomy (DP). Methods A total of 165 patients who underwent stapled DP between July 2018 and March 2024 were included.
Shigeaki Kurihara, Kenjiro Kimura, Genki Watanabe, Ryota Tanaka, Sadaaki Nishimura, Jun Tauchi, Masahiko Kinoshita, Kohei Nishio, Hiroji Shinkawa, Takeaki Ishizawa   +9 more
wiley   +1 more source

Visceral Adipose Tissue as an Independent Predictor of Severe Post‐ERCP Pancreatitis: A Multicenter Retrospective Cohort Study

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Acute pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP), known as post‐ERCP pancreatitis (PEP), is a major adverse event. Although risk factors for PEP incidence have been widely studied, factors associated with severe PEP remain unclear.
Shinya Uemura, Takuji Iwashita, Takuya Koizumi, Yosuke Ohashi, Shota Iwata, Akinori Maruta, Keisuke Iwata, Masahito Shimizu   +7 more
wiley   +1 more source

Infected Walled-Off Pancreatic Necrosis Treated with Multiple-Gateway EUS-Guided Drainage

GE: Portuguese Journal of Gastroenterology, 2021
Margarida Flor de Lima, Nuno Nunes, Carolina Chálim Rebelo, Diogo Bernardo Moura, Ana Catarina Rego, Maria Antónia Duarte   +5 more
doaj   +1 more source

Nutritional and environmental determinants of maturation and disruption of the early life gut microbiome: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract The first 1000 days of life represent a critical window for gut microbiome assembly, with lifelong implications for child growth, immune development, and disease risk. This review synthesizes evidence on maternal, perinatal, and especially nutritional factors that influence early‐life intestinal colonization and highlights the consequences of ...
Carly Burow, Romy Shenderey, Fariha Chowdhury, Nyah Shah, Nikhil Pai   +4 more
wiley   +1 more source

ACUTE PANCREATITIS: CURRENT UNDERSTANDING OF DEVELOPMENT, DIAGNOSIS, AND TREATMENT

Фундаментальная и клиническая медицина, 2017
Here I discuss the recent data on epidemiology, development, diagnosis, and treatment of acute pancreatitis, with the particular focus on its complications.
VALERIY I. Podoluzhnyi
doaj  

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Triglyceride‐Related Indices and Risk of Acute Pancreatitis: A Prospective Study in UK Biobank

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Triglyceride‐related indices, including triglyceride‐glucose (TyG), TyG related to body mass index (TyG‐BMI), TyG related to waist circumference (TyG‐WC), TyG related to waist‐to‐height ratio (TyG‐WHtR), atherogenic index of plasma (AIP), cardiometabolic index (CMI), visceral adiposity index (VAI), and lipid accumulation product (LAP), are ...
Jing‐Bo Li, Yu‐Jiao Zhu, Yang‐Jie Liao, Jia‐Yi Wang   +3 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Heterogeneity Analyzed by CT‐Based Habitat Analysis for Clinical Management of Cancers: A Narrative Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tumors are highly heterogeneous, and whole‐lesion radiomics analysis is a popular method for extracting texture features that reflect this heterogeneity, which can be used to build models for cancer diagnosis, staging, therapy response evaluation, and prognosis prediction.
Yang Zhang, Zhi‐Yan Jin, Min‐Ying Lydia Su   +2 more
wiley   +1 more source