Results 81 to 90 of about 24,147 (280)

Is endoscopic necrosectomy the way to go?

Gastrointestinal Intervention, 2016
Pancreatic necrosis with the formation of walled-off collections is a known complication of severe acute pancreatitis. Infected necrotic pancreatic collections are associated with a high mortality rate.
James Weiquan Li, Tiing Leong Ang
doaj   +1 more source

Percutaneous Catheter-directed Debridement of Infected Pancreatic Necrosis: Results in 20 Patients

, 1998
To evaluate the usefulness of transcatheter debridement of infected pancreatic necrosis. Transcatheter debridement was performed on 20 patients who ranged in age from 20 to 78 years during the 8-year study period.
Jose Yrizarry, Echenique, Ana M, Russell, Edward, Danny Sleeman, Edward Russell, Guerra, Jorge J, Hemy Huson, Ana M. Echenique, Thomas Scagnelli, Scagnelli, Thomas, Jorge J. Guerra, Huson, Hemy, Yrizarry, Jose, V. Javier Casillas, Sleeman, Danny, Casillas, V. Javier   +15 more
core   +1 more source

Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

Arthritis &Rheumatology, EarlyView.
Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan, Emma R. Dorris, Maria Inês Pimenta, Jemma Falkov, Matthew Fisher, Sam Pledger, Hector Devey, Munitta Muthana, Denis C. Shields, Richard E. Mains, Betty A. Eipper, Christopher D. Buckley, Anthony G. Wilson   +12 more
wiley   +1 more source

Minimally invasive treatment of infected pancreatic necrosis

Gastroenterology Review, 2014
Infected pancreatic necrosis is a challenging complication that worsens prognosis in acute pancreatitis. For years, open necrosectomy has been the mainstay treatment option in infected pancreatic necrosis, although surgical debridement still results in high morbidity and mortality rates.
Wroński, Marek, Cebulski, Włodzimierz, Słodkowski, Maciej, Krasnodębski, Ireneusz W.   +3 more
openaire   +2 more sources

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Instrumental diagnosis of infected forms of pancreatic necrosis

, 2023
Через шкірна тонкоголкова аспіраційна біопсія парапанкреатичної клітковини під УЗ-контролем з мікробіологічними дослідженням біоматеріалу з метою верифікації гнійно-септичних ускладнень панкреонекрозу виконана 46 пацієнтам хворим на гострий некротизуючий
Меркулов, Андрій Олексійович, Шевченко, Олександр Миколайович, Кулик, Ігор Анатолійович, Білодід, Є. О.   +3 more
core   +1 more source

A descriptive case series of hepatotoxicity associated with CFTR modulators and possible relevance of pharmacogenetic polymorphisms in cystic fibrosis patients

British Journal of Clinical Pharmacology, EarlyView.
Cystic fibrosis transmembrane conductance regulator (CFTR) modulators are widely used in patients with cystic fibrosis and significantly improve respiratory function and quality of life. However, their effectiveness may be limited by liver damage, which sometimes leads to treatment discontinuation, and the mechanisms underlying this remain poorly ...
Clara Laffitte Redondo, Venceslas Bourdin, Abd El Kader Ait Tayeb, Sihem Benaboud, Inès Martins, Caroline Joyau, Myriam Benhamida, Isabelle Sermet‐Gaudelus, Clémence Martin, Pierre Régis Burgel, Céline Verstuyft, Laurent Chouchana, Estelle Ayme‐Dietrich   +12 more
wiley   +1 more source

Antibiotic-associated Enterococcus expansion in the gastrointestinal tract precedes infected necrosis in acute necrotizing pancreatitis

Gut Microbes
Infected pancreatic necrosis complicates 30% of necrotizing pancreatitis cases, with intestinal bacterial translocation as the presumed mechanism.
Fons F. van den Berg, Hannah S. Pauw, Hester C. Timmerhuis, Marc G. Besselink, Yama Issa, Marco J. Bruno, Pieter Jan de Jonge, Harry van Goor, Erwin J. M. van Geenen, Rutger Quispel, Wim van de Vrie, Adriaan Tan, Muhammed Hadithi, Niels G. Venneman, Rogier P. Voermans, Jeroen M. Jansen, Ben J. Witteman, Matthijs P. Schwartz, Roy L. J. van Wanrooij, Alexander C. Poen, Peter van Duijvendijk, Marie-Paule Anten, Tessa E. H. Römkens, Elske Sieswerda, Merel M. Tielemans, Jeanin E. van Hooft, Marja A. Boermeester, Robert C. Verdonk, Hjalmar C. van Santvoort   +28 more
doaj   +1 more source

Endoscopic necrosectomy for infected pancreatic necrosis

, 2012
This review details the indications, technique, and outcomes of endoscopic necrosectomy for the treatment of pancreatic necrosis. Data from 14 previous reports revealed that the rate of complete resolution of pancreatic necrosis with endoscopic ...
Yasuda, Ichiro
core   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source