Results 61 to 70 of about 49,177 (304)
Medicina, 2022 Background and Objectives: The course and clinical outcomes of acute pancreatitis (AP) are highly variable. Up to 20% of patients develop pancreatic necrosis. Extent and location of it might affect the clinical course and management.
Inga Dekeryte +4 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advanced Science, EarlyView.This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin +14 more
wiley +1 more source
Management of infected pancreatic necrosis: state of the art
Revista do Colégio Brasileiro de CirurgiõesPancreatic necrosis occurs in 15% of acute pancreatitis. The presence of infection is the most important factor in the evolution of pancreatitis. The diagnosis of infection is still challenging.
Roberto Rasslan +4 more
doaj +1 more source
Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]
, 2017 Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola +3 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu +12 more
wiley +1 more source
A new algorithm for surgical treatment of infected pancreatic necrosis
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровьеObjective: to improve treatment outcomes in patients with infected pancreatic necrosis through the rational use of minimally invasive technologies. Materials and methods.
E. A. Korymasov +3 more
doaj +1 more source
Endoscopic Necrosectomy as Treatment for Infected Pancreatic Necrosis [PDF]
European Medical Journal Gastroenterology, 2013 Necrotising pancreatitis can be life-threatening, but the introduction of endoscopic necrosectomy has led to a tremendous reduction of lethality. This review describes the technique and role of this method between conservative treatment and other ...
Dr. Christian Jürgensen
doaj
Current Status of Direct Endoscopic Necrosectomy
Proceedings of Singapore Healthcare, 2012 The management of pancreatic necrosis has evolved. Sterile necrosis is now managed conservatively. Intervention is generally required for infected necrosis but is now deferred until four weeks after disease onset in order to permit encapsulation and ...
Tiing Leong Ang FRCP (Edin), FAMS (Gastroenterology)
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs +4 more
wiley +1 more source