Results 41 to 50 of about 49,177 (304)

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone [PDF]

, 2020
Alterations in the NRF2/KEAP1 pathway result in the constitutive activation of NRF2, leading to the aberrant induction of antioxidant and detoxification enzymes, including NQO1.
Boothman, David A., DeNicola, Gina M., Elkins, Cody M., Falzone, Aimee, Haura, Eric B., Prieto-Farigua, Nicolas, Torrente, Laura   +6 more
core   +1 more source

LOCAL ANTIBACTERIAL TREATMENT IN PATIENTS WITH INFECTED PANCREATIC WALLED-OFF NECROSIS: A SYSTEMATIC REVIEW

Клінічна та профілактична медицина
Introduction. Systemic antibacterial treatment in patients with infected pancreatic necrosis often fails to resolve the infection due to impaired penetration in necrotic areas.
Nizar R. Kerbazh, Daniel de la Iglesia, Jose Larino-Noia, Julio Iglesias-Garcia, Serhii I. Panasenko, Juan E. Dominguez-Munoz   +5 more
doaj   +1 more source

EUS-Guided Multitransgastric Endoscopic Necrosectomy for Infected Pancreatic Necrosis with Noncontagious Retroperitoneal and Peritoneal Extension

Gut and Liver, 2010
Endoscopic necrosectomy was introduced as a safe and effective treatment modality for infected pancreatic necrosis. Although there have been many reports of endoscopic drainage of retroperitoneal pancreatic necrosis, the optimal endoscopic management of ...
doaj   +1 more source

The complex treatment of acute pancreatitis using miniinvasive surgical treatment

Zaporožskij Medicinskij Žurnal, 2015
Nowadays methods used in acute pancreatitis diagnostic do not allow to find the most optimal indications, terms of surgical drainage approaches in surgical treatment of acute pancreatitis. Aim.
G. I. Ohrimenko, N. G. Golovko, V. A. Grushka, T. S. Gavrilenko, P. G. Kocherov   +4 more
doaj   +1 more source

Transgastric Pancreatic Necrosectomy: How I Do It [PDF]

, 2015
Necrotizing pancreatitis is a serious medical problem that often requires intervention to debride necrotic pancreatic and peripancreatic tissue. Recently, minimally invasive approaches have been applied to pancreatic necrosectomy.
House, Michael G., Jester, Andrea L., Nakeeb, Attila, Zyromski, Nicholas J.   +3 more
core   +1 more source

Early Versus Delayed Minimally Invasive Intervention for Infected Pancreatic Necrosis -

Translation, 2023
Please view the PDF to see the formatted meeting abstract.  
Sami Ghazaleh
doaj   +1 more source

Selective precipitation reaction: a novel diagnostic test for tissue pathology in Atlantic Salmon, Salmo salar, infected with Salmonid Alpha-Virus (SAV3) [PDF]

, 2017
While investigating biomarkers for infection with salmonid alphavirus (SAV), the cause of pancreas disease (PD), a selective precipitation reaction (SPR) has been discovered in serum which could be an on-farm qualitative test and an in-laboratory ...
Adams, Asenjo, Biacchesi, Braceland, Braceland, Braceland, Ceciliani, Coeurdacier, Cray, Dawson, Heide, Kibenge, Larsson, Lerfall, Mayeux, McLoughlin, McLoughlin, Mcloughlin, McVicar, Munro, Taksdal   +20 more
core   +1 more source

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. [PDF]

, 2019
There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these
Atkinson, Mark A, Dang, Hoa, Kaufman, Daniel L, Sun, Ren, Tian, Jide, Wu, Ting-Ting, Yong, Jing   +6 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Clinical aspects of diagnosis and prognosis of acute necrotic pancreatitis

Хірургія дитячого віку
Aim - to evaluate diagnostic markers of acute pancreatitis. Materials and methods. The study was conducted in the period from 2014 to 2023 and was based on the assessment of the severity of acute pancreatitis (AP) in 237 patients.
A.I. Banadyga, N.V. Banadyha
doaj   +1 more source