Results 31 to 40 of about 1,184,326 (242)

Decreasing use of pancreatic necrosectomy and NSQIP predictors of complications and mortality

open access: yesWorld Journal of Emergency Surgery, 2022
Background Surgical pancreatic necrosectomy (SPN) is an option for the management of infected pancreatic necrosis. The literature indicates that an escalating, combined endoscopic, interventional radiology and minimally invasive surgery “step-up ...
Amy E. Liepert   +8 more
doaj   +1 more source

Complex Application of Minimally Invasive Methods for the Treatment of Complicated Acute Severe Pancreatitis

open access: yesНеотложная медицинская помощь, 2022
Percutaneous interventions for the purpose of sanation of cavities of pancreatogenic destruction can be one of the ways to treat pancreatic necrosis. This leads to a rapid cleansing of the cavities and is an objective method of monitoring the stages of ...
M. L. Rogal   +7 more
doaj   +1 more source

Cultured pathogens in infected pancreatic necrosis.

open access: yes, 2016
Cultured pathogens in infected pancreatic necrosis.
Sebastian Rasch (448322)   +27 more
core   +1 more source

Infected pancreatic necrosis increases the severity of experimental necrotizing pancreatitis in mice

open access: yes, 2013
OBJECTIVE Infection of pancreatic necrosis in necrotizing pancreatitis increases the lethality of patients with acute pancreatitis. To examine mechanisms underlying this clinical observation, we developed and tested a model, in which primary infection ...
Wittel, Uwe A.   +5 more
core   +1 more source

The complex treatment of acute pancreatitis using miniinvasive surgical treatment

open access: yesZaporožskij Medicinskij Žurnal, 2015
Nowadays methods used in acute pancreatitis diagnostic do not allow to find the most optimal indications, terms of surgical drainage approaches in surgical treatment of acute pancreatitis. Aim.
G. I. Ohrimenko   +4 more
doaj   +1 more source

Minimally invasive strategy of infected pancreatic necrosis

open access: yesВестник хирургии имени И.И. Грекова
Treatment of patients with pancreatic necrosis remains one of the most urgent and complex tasks in emergency surgery. The need for further research in this area is dictated by a high mortality rate (15–70 %).
D. V. Cherdancev   +3 more
doaj   +1 more source

Managing infected pancreatic necrosis

open access: yes, 2018
The management of infected pancreatic necrosis has historically been based on early, open necrosectomy, associated with significant mortality. In recent years, an evidence based transformation has occurred towards the step-up approach consisting of ...

core   +1 more source

Infected pancreatic necrosis: minimizing the cut

open access: yes, 2010
The challenge for the pancreatologist managing patients with infected pancreatic necrosis is to devise a treatment algorithm that enables recovery but at the same time limits the morbidity and mortality.
McKay, Colin   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

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