Results 31 to 40 of about 1,184,326 (242)
Decreasing use of pancreatic necrosectomy and NSQIP predictors of complications and mortality
Background Surgical pancreatic necrosectomy (SPN) is an option for the management of infected pancreatic necrosis. The literature indicates that an escalating, combined endoscopic, interventional radiology and minimally invasive surgery “step-up ...
Amy E. Liepert +8 more
doaj +1 more source
Percutaneous interventions for the purpose of sanation of cavities of pancreatogenic destruction can be one of the ways to treat pancreatic necrosis. This leads to a rapid cleansing of the cavities and is an objective method of monitoring the stages of ...
M. L. Rogal +7 more
doaj +1 more source
Cultured pathogens in infected pancreatic necrosis.
Cultured pathogens in infected pancreatic necrosis.
Sebastian Rasch (448322) +27 more
core +1 more source
Infected pancreatic necrosis increases the severity of experimental necrotizing pancreatitis in mice
OBJECTIVE Infection of pancreatic necrosis in necrotizing pancreatitis increases the lethality of patients with acute pancreatitis. To examine mechanisms underlying this clinical observation, we developed and tested a model, in which primary infection ...
Wittel, Uwe A. +5 more
core +1 more source
The complex treatment of acute pancreatitis using miniinvasive surgical treatment
Nowadays methods used in acute pancreatitis diagnostic do not allow to find the most optimal indications, terms of surgical drainage approaches in surgical treatment of acute pancreatitis. Aim.
G. I. Ohrimenko +4 more
doaj +1 more source
Minimally invasive strategy of infected pancreatic necrosis
Treatment of patients with pancreatic necrosis remains one of the most urgent and complex tasks in emergency surgery. The need for further research in this area is dictated by a high mortality rate (15–70 %).
D. V. Cherdancev +3 more
doaj +1 more source
Managing infected pancreatic necrosis
The management of infected pancreatic necrosis has historically been based on early, open necrosectomy, associated with significant mortality. In recent years, an evidence based transformation has occurred towards the step-up approach consisting of ...
core +1 more source
Infected pancreatic necrosis: minimizing the cut
The challenge for the pancreatologist managing patients with infected pancreatic necrosis is to devise a treatment algorithm that enables recovery but at the same time limits the morbidity and mortality.
McKay, Colin +5 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source

