Course of pancreatic necrosis on a background of major duodenal papilla stone
Aim of investigation. To estimate course of biliary pancreatic necrosis (PN) on a background of an «impacted» stone of major duodenal papilla in comparison to pancreatic necrosis of alimentary origin.Material and methods. Treatment results of 76 patients
S. V. Mikhaylusov +2 more
doaj
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu +2 more
wiley +1 more source
Risk Factors and Outcomes of Multidrug-Resistant Bacteria Infection in Infected Pancreatic Necrosis Patients. [PDF]
Lu J +10 more
europepmc +1 more source
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi +8 more
wiley +1 more source
Evaluating the role of the Minimal Incision Retroperitoneal Necrosectomy (MIRN) in the management of infected pancreatic necrosis: Experience from a tertiary care center. [PDF]
Avudiappan M +5 more
europepmc +1 more source
Effects of proton therapy on the tumor immune system and clinical implications: A review
Proton therapy is a novel radiotherapy technique. We review four aspects of proton therapy: application in various tumors, effects on the tumor immune system, combination with other therapies, and future challenges. By presenting these aspects in this review, we aim to inspire clinical interventions.
Rundong Liu +5 more
wiley +1 more source
Prediction of infected pancreatic necrosis in acute necrotizing pancreatitis by the modified pancreatitis activity scoring system. [PDF]
Mao W +14 more
europepmc +1 more source
Catechins and Their Effect on the Gut Microbiome in Health and Cancer
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika +5 more
wiley +1 more source
Impact of multiple drug-resistant Gram-negative bacterial bacteraemia on infected pancreatic necrosis patients. [PDF]
Wu D +7 more
europepmc +1 more source

