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Etiology and pathogenesis of infected pancreatic necrosis

Khirurgiya. Zhurnal im. N.I. Pirogova, 2022
Modern literature data confirm the central role of intestinal barrier complex not only as a target in acute necrotizing pancreatitis, but also as a trigger for septic complications. Intra-abdominal hypertension, endothelial dysfunction and gut microbiome changes following necrotizing pancreatitis might have an independent impact on acute intestinal ...
Yu.S. Vinnik   +2 more
openaire   +2 more sources

Endoscopic transluminal drainage of infected pancreatic necrosis

Khirurgiya. Zhurnal im. N.I. Pirogova, 2021
To report initial experience of endoscopic transluminal drainage of infected pancreatic necrosis.There were 8 patients with acute severe pancreatitis and large-focal pancreatic necrosis who underwent transluminal drainage of destruction zones for the period from December 2018 to October 2019.Transluminal drainage of pancreatogenic destruction zones in ...
Yu S, Teterin   +5 more
openaire   +2 more sources

Infected pancreatic necrosis

International journal of pancreatology, 1994
We have attempted here to address the problems relating to the pathophysiology, identification and treatment of IPN. The diagnostic role of radiology and of examination of culture samples obtained under its guidance is stressed as the gold standard in all cases where clinical findings have yielded a suspicion of superinfection.
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A retroperitoneal approach for infected pancreatic necrosis

Scandinavian Journal of Gastroenterology, 2012
Acute pancreatitis remains associated with a high rate of complication and death. The surgery strategy for proven or suspected infected necrosis is controversial.The present study reviews the medical records of 9,421 patients admitted with the diagnosis of acute pancreatitis from 2002 to 2009.The medical records of 9,421 admitted patients diagnosed ...
Qiang, Guo   +3 more
openaire   +2 more sources

Management of infected pancreatic necrosis

Current Gastroenterology Reports, 2008
The past two decades have seen major advances in the understanding and clinical management of acute pancreatitis, yet it still lacks a specific treatment, and management is largely supportive and reactive. Surgery is seeing a diminishing role in the early phase of acute pancreatitis but still predominates in the management of infected pancreatic ...
openaire   +2 more sources

Endoscopic transluminal drainage for infected pancreatic necrosis

Khirurgiya. Zhurnal im. N.I. Pirogova, 2022
To evaluate the effectiveness of intraluminal drainage of acute fluid accumulations for infected pancreatic necrosis.There were 848 patients with acute pancreatitis between January 2018 and December 2020 at the Sklifosovsky Research Institute for Emergency Care. Necrotizing pancreatitis was detected in 232 (27.4%) patients.
Yu S, Teterin   +6 more
openaire   +2 more sources

Is Severity of Necrotizing Pancreatitis Increased in Extended Necrosis and Infected Necrosis?

Pancreas, 2002
We previously reported that organ failure occurs in 50% of patients with necrotizing pancreatitis, that extended pancreatic necrosis (greater than 50% necrosis) is not associated with an increased prevalence of organ failure or infected necrosis, and that the prevalence of organ failure is similar in sterile necrosis and infected necrosis.
Alexander, Perez   +8 more
openaire   +2 more sources

Pancreatic abscess and infected pancreatic necrosis

Digestive Diseases and Sciences, 1987
Local septic complications in acute pancreatitis need to be exactly characterized and defined in order to develop improved concepts for their prevention, early diagnosis, and therapy. While up to now all local septic complications have been termed abscesses, the present study for the first time delineates the morphologic, clinical, and laboratory ...
R, Bittner   +3 more
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Minimally Invasive Debridement for Infected Pancreatic Necrosis

Journal of Gastrointestinal Surgery, 2019
Necrotizing pancreatitis has historically been treated with open necrosectomy, which carries a high morbidity and mortality rate. More recently, there has been a shift towards endoscopic and percutaneous approaches employed as part of a minimally invasive step-up approach.
Zhi Ven Fong, Peter J. Fagenholz
openaire   +2 more sources

Sterile and Infected Pancreatic Necrosis

2014
Acute necrotizing pancreatitis is a complication of acute pancreatitis that carries high morbidity and mortality. The majority of patients have sterile necrosis, which can be managed conservatively. However, in contrast, patients with infected necrosis often require drainage or debridement.
Elham Afghani, Vikesh K. Singh
openaire   +1 more source

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