Results 101 to 110 of about 5,236,282 (261)

Immunodetection of NETs in paraffin-embedded tissue

Frontiers in Immunology, 2016
The pathogenic potential of NETs was recently described and their detection in tissue could serve as a prognostic marker. NETs are delicate and filigree structures, hence good tissue preservation is essential for their detection.
Volker Brinkmann, Ulrike Abu Abed, Ulrike Abu Abed, Christian Goosmann, Arturo Zychlinsky   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Secondary antifungal prophylaxis in allogeneic hematopoietic stem cell transplant recipients with invasive fungal infection. [PDF]

, 2018
Invasive fungal infection (IFI) is a major cause of morbidity and mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. A previous history of IFI is not an absolute contraindication for allo-HSCT, particularly in the era
Yegin, Zeynep A, Zübeyde N Özkurt, Yildirim, Zeki, Ayşe Kalkanci, Zeki Yildirim, Erbaş, Gonca, Pepeler, Mehmet S, Kalkanci, Ayşe, Tunçcan, Özlem G, Özkurt, Zübeyde N, Gonca Erbaş, Yildiz, Şeyma, Köktürk, Nurdan, Şeyma Yildiz, Zeynep A Yegin, Nurdan Köktürk, Mehmet S Pepeler, Özlem G Tunçcan, GÜZEL TUNÇCAN, ÖZLEM, ÖZKURT, ZÜBEYDE NUR, YEGİN, ZEYNEP ARZU, Pepeler, Mehmet Sezgin and Yildiz, Seyma and Yegin, Zeynep Arzu and Ozkurt, Zubeyde Nur and Tunccan, Ozlem Guzel and Erbas, Gonca and Kokturk, Nurdan and Kalkanci, Ayse and Yildirim, Zeki, Pepeler, Mehmet Sezgin   +22 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The role of intestinal dendritic cells and the microbiota during oral Salmonella infection [PDF]

, 2015
The intestinal pathogen Salmonella causes millions of infections per year worldwide. The immune response to these bacteria involves interactions between several cell types via specific molecules and is under the influence of the intestinal microbiota ...
Fernandez, Maria, Maria eFernandez-Santoscoy, Fernandez-Santoscoy, Maria, Tam, Miguel A, Ulf Alexander Wenzel, Wick, Mary Jo, Pia Tegtmeyer, Tegtmeyer, Pia,, Maria Fernandez-Santoscoy, Wenzel, Ulf Alexander, Pia eTegtmeyer, Mary Jo eWick, Tegtmeyer, Pia, Mary Jo Wick, Fernández-Santoscoy, Maria,, Wick, Mary Jo,, Wenzel, Ulf Alexander,, Miguel A. Tam, Tam, M. A.   +18 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Infection-related mortality.

, 2019
Infection-related mortality.
Kumiko Torisu (5278769), Shigeru Tanaka (40073), Kazuhiko Tsuruya (636724), Hidetoshi Kanai (6490667), Toshiaki Nakano (27092), Yuta Matsukuma (6490664), Hiroaki Tsujikawa (6490661), Takanari Kitazono (483472)   +7 more
core   +1 more source

Implementing change in infection control practice : an action research study in two intensive care units. [PDF]

, 1999
The increased emergence of bacterial resistance to antibiotics means that primary prevention of all hospital-acquired infections is essential, but ensuring that infection control practice is evidence-based requires reliable measurement of endemic ...
Sproat, Louise Jane
core   +2 more sources