Results 131 to 140 of about 7,251,989 (335)

Nosocomial infections and infection control

open access: yesMedicine, 2017
Abstract Nosocomial infections are a leading cause of avoidable harm in hospital patients and a substantial, unnecessary drain on healthcare resources. They are frequently caused by bacteria that are resistant to multiple antibiotics, and the treatment of nosocomial infections contributes to the selection of resistant bacteria.
openaire   +2 more sources

Leprosy and tuberculosis concomitant infection: a poorly understood, age-old relationship [PDF]

open access: yes, 2014
Historically, archaeological evidence, post-mortem findings and retro- spective analysis of leprosy institutions’ data demonstrates a high observed incidence of concomitant infection with leprosy and tuberculosis (TB).
Anjum, V   +7 more
core  

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Presymptomatic, asymptomatic and post-symptomatic transmission of SARS-CoV-2: joint British Infection Association (BIA), Healthcare Infection Society (HIS), Infection Prevention Society (IPS) and Royal College of Pathologists (RCPath) guidance

open access: yesBMC Infectious Diseases, 2022
Moira A. Mugglestone   +12 more
doaj   +1 more source

Adherence to national recommendations for the control of multidrug-resistant microorganisms in Swiss acute care hospitals – an updated national survey

open access: yesAntimicrobial Resistance and Infection Control
Summary Background Screening patients at risk of multidrug-resistant organism (MDRO) carriage is a cornerstone of infection prevention and control to identify carriers and prevent transmission. In 2021, the Swiss Centre for Infection Prevention Swissnoso
Andrea C. Büchler   +15 more
doaj   +1 more source

Cutting the Cord: A Case of Late Presenting Driveline Infection [PDF]

open access: yes, 2020
Ventricular assist device (VAD) related infection, specifically driveline infection, is a common complication after VAD implantation. A 45-year old patient with a delayed skin infection at the site of the original driveline nearly one year after VAD ...
Eyadiel, Lauren   +2 more
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

TracrRNA reprogramming enables direct PAM-independent detection of RNA with diverse DNA-targeting Cas12 nucleases

open access: yesNature Communications
Many CRISPR-Cas immune systems generate guide (g)RNAs using trans-activating CRISPR RNAs (tracrRNAs). Recent work revealed that Cas9 tracrRNAs could be reprogrammed to convert any RNA-of-interest into a gRNA, linking the RNA’s presence to Cas9-mediated ...
Chunlei Jiao   +8 more
doaj   +1 more source

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