Results 141 to 150 of about 8,269,565 (363)

Guidance on public reporting of healthcare-associated infections: recommendations of the Healthcare Infection Control Practices Advisory Committee [PDF]

open access: yes
"Embargoed until Monday, February 28, 2005 at 12:30 pm."Since 2002, 4 states have enacted legislation that requires health care organizations to publicly disclose health care-associated infection (HAI) rates.
Hospital Infection Control Practices Advisory Committee (U.S.)
core  

Adherence to national recommendations for the control of multidrug-resistant microorganisms in Swiss acute care hospitals – an updated national survey

open access: yesAntimicrobial Resistance and Infection Control
Summary Background Screening patients at risk of multidrug-resistant organism (MDRO) carriage is a cornerstone of infection prevention and control to identify carriers and prevent transmission. In 2021, the Swiss Centre for Infection Prevention Swissnoso
Andrea C. Büchler   +15 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Evaluation of a new in-clinic test system to detect feline immunodeficiency virus and feline leukemia virus infection

open access: yes, 2010
Background: Many in-house tests for the diagnosis of feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) infection are licensed for use in veterinary practice.
Strategic Infection Biology   +6 more
core  

Sharps injuries and bloodborne pathogen exposure among healthcare workers: a 5-year surveillance in a teaching hospital in Singapore

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Introduction: Bloodborne pathogens’ exposures are defined as injuries to contaminated sharps and exposures to patients’ blood or body fluids continue to present risks to healthcare workers (HCWs).
Zhang Zhimin   +8 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Microscopic detection of hemozoin in peripheral leukocytes fails to indicate plasmodial placental infection in pregnant women

open access: yes, 2017
Introduction: Malaria in pregnancy very often includes gestational (parasites in maternal peripheral blood) and placental (parasites in placental blood) infection, but the later condition can only be detected after delivery.
Eliana Arango   +9 more
core   +1 more source

Clinical Significance and Functional Insights of Tesmin in Hepatocellular Carcinoma

open access: yesGenetics Research
Background. Tesmin, a 60 kDa protein encoded by the metallothionein-like 5 (MTL5) gene, plays a vital role in spermatogenesis and oogenesis. Recent research has unveiled its potential involvement in malignancies, although its impact on HCC remains poorly
Lijun Cao, Lin Zhang, Siyu Liu, Xue Wang
doaj   +1 more source

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