Results 71 to 80 of about 3,746,616 (308)

Summary of Infection Prevention Practices in Dental Settings: Basic Expectations for Safe Care [PDF]

This document is a summary guide of basic infection prevention recommendations for all dental health care settings. These include traditional settings such as private dental practices, dental clinics, dental schools and educational programs (including ...

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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The First Reported Foodborne Botulism Outbreak in Riyadh, Saudi Arabia: Lessons Learned

Journal of Epidemiology and Global Health
Background Botulism has not been previously reported in the Kingdom of Saudi Arabia. This rare and sometimes fatal foodborne illness is caused by neurotoxins and primarily results from consuming home-canned fruits, vegetables, dairy, and seafood products
Nadeem Gul Dar, Sarah H. Alfaraj, Khulood Naser Alboqmy, Nazia Khanum, Faleh Alshakrah, Hassan Abdallah, Mohammad Hosni Badawi, Ohoud Mohammed Alharbi, Khadijh Ahmed Alshiekh, Abdullah M Alsallum, Ahmed Hassan Shrahili, Zeidan A Zeidan, Zaki Abdallah, Ahmed Ali Majrashi, Ziad A. Memish   +14 more
doaj   +1 more source

Environmental Fungal Contamination Characterization of Three Inpatient Units Utilizing Optimized Detection Methods

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Environmental sampling and detection methods for fungi in healthcare settings are not well-established. We previously refined methods for fungal sampling and detection in a controlled laboratory environment and aimed to validate them in a ...
Bobby Warren, Guerbine Fils-aime, Amanda Graves, Aaron Barrett, Matthew Steigel, Becky Smith, Ilan Schwartz, Deverick Anderson   +7 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Infection control in healthcare personnel : infrastructure and routine practices for occupational infection prevention and control services [PDF]

Updated: October 2019This document, Infection Control in Healthcare Personnel: Infrastructure and Routine Practices for Occupational Infection Prevention and Control Services, is an update of four sections of Part I of the Guideline for infection control

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PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Assessing social support’s mediating effects on rational antimicrobial prescribing: a structural equation modeling study of healthcare professionals’ behavior

Scientific Reports
Antimicrobial resistance is a critical global health challenge, requiring effective strategies to promote rational antimicrobial prescribing among healthcare professionals.
Le Han, Xiao Liu, Ying Liu, Yue Chang, Lijun Ma, Jie Ren, Xiaosong Wang, Yujuan Long, Baokun Dong, Yunshuang Liu, Li Ren, Yuan Zhou   +11 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Prevention of intravascular catheter-related infection in Ireland

, 2010
e Strategy for the Control of Antimicrobial Resistance in Ireland (SARI) National Committee.established a subcommittee to produce national guidelines on the prevention of intravascular catheter– related infection.
SARI Prevention of Intravascular Catheter-related Infection Sub-Committee
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