Results 111 to 120 of about 2,928,024 (297)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Impact of creatinine clearance on helicobacter pylori eradication rate in patients with peptic ulcer disease [PDF]
, 2015 Introduction. Gastrointestinal complaints are common in patients with kidney failure. The aim of this study was to investigate the effect of creatinine clearance on Helicobacter pylori (HP) eradication rate in patients with peptic ulcer disease ...
Alimadadi, M. +6 more
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Frontiers in Public HealthObjectivesThe COVID-19 pandemic highlighted the need for data-driven decision making in managing public health crises. This study aims to extend previous research by incorporating infection-related mortality (IRM) to evaluate the discrepancies between seroprevalence data and infection rates reported to the Centers for Disease Control and Prevention ...
Eric W. Ford +7 more
openaire +3 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
AntibioticsBackground/Objectives: To evaluate the effectiveness of local antibiotic prophylaxis (e.g., powder, bone cement, intraosseous injection) in reducing periprosthetic joint infections (PJI) and deep wound infections in adults undergoing primary joint ...
Chia-Yu Lin +6 more
doaj +1 more source
, 2017 Some viruses, such as human immunodeficiency virus, can infect several types of cell populations. The age of infection can also affect the dynamics of infected cells and production of viral particles.
Cervantes-Pérez, Ángel +1 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
DEATH RATE IN ACUTE INFECTIONS [PDF]
Journal of the American Medical Association, 1916 Through the courtesy of the bureau of health, I have secured a record of the deaths from these acute infections during the past five years; and, while this record may possibly be incomplete, owing to the failure of physicians to recognize or report some cases, yet the study of these statistics will lead to several interesting conclusions.
openaire +1 more source