Results 101 to 110 of about 1,488,818 (255)

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini   +9 more
wiley   +1 more source

Neisseria gonorrhoeae conjunctivitis in a prepuberal girl a dilemma

open access: yesDST, 2018
Sexually transmitted infections (STIs) are a public health issue of global concern and frequently lead to important sequelae if not diagnosed and properly treated.
Maria Ivete Castro Boulos   +3 more
doaj  

Large deviations for infectious diseases models [PDF]

open access: yesarXiv, 2016
We establish large deviation estimates for Poisson driven models of infectious disease, and apply those estimates to the time of exit from the basin of attraction of an endemic equilibrium. We apply our results to the classical SIRS model.
arxiv  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

Investigating cutaneous tuberculosis and nontuberculous mycobacterial infections in a Department of Dermatology, Beijing, China: a comprehensive clinicopathological analysis

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundCutaneous tuberculosis (CTB) and nontuberculous mycobacteria (NTM) infections present considerable diagnostic and therapeutic challenges.
Xin-Yu Wang   +3 more
doaj   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

open access: yesMolecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park   +6 more
wiley   +1 more source

Marker-assisted genotyping of eBSV alleles in banana [PDF]

open access: yes, 2013
The genome of banana (Musa sp.) harbours multiple integrations of Banana streak viruses(eBSVs), although integration is not required for the replication of cognate viruses.
Chabannes, Matthieu   +6 more
core  

Transmission of Mycobacterium tuberculosis Beijing Strains, Alberta, Canada, 1991–2007

open access: yesEmerging Infectious Diseases, 2013
Beijing strains are speculated to have a selective advantage over other Mycobacterium tuberculosis strains because of increased transmissibility and virulence.
Deanne Langlois-Klassen   +6 more
doaj   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

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