Results 91 to 100 of about 292,148 (372)

Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19?

American Journal of Tropical Medicine and Hygiene, 2020
. The COVID-19 pandemic, caused by SARS-CoV-2, have surpassed 5 million cases globally. Current models suggest that low- and middle-income countries (LMICs) will have a similar incidence but substantially lower mortality rate than high-income countries ...
J. Gutman, N. Lucchi, P. Cantey, L. Steinhardt, Aaron M. Samuels, M. Kamb, B. Kapella, P. Mcelroy, V. Udhayakumar, K. Lindblade   +9 more
semanticscholar   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

Advanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo, Yuce Peng, Guozhi Zhao, Zhesheng Cheng, Minghao Luo, Dingyi Lv, Shuting Chang, Na Li, Yanyao Huang, Xunjia Li, An He   +10 more
wiley   +1 more source

SALIVARY SPECIFIC IgE TO D1 AND G6 IN PATIENTS WITH RHINITIS WITH OR WITHOUT S. AUREUS COLONIZATION

Problems of Infectious and Parasitic Diseases
Globally, allergic rhinitis impacts roughly 25% of children and 40% of adults. Immunoglobulin E (IgE) plays a crucial part in allergic inflammation, with two sources: spontaneously produced IgE, and IgE stemming from reactions to environmental allergens.
Diana Hristova, Antoaneta Decheva, Deyan Donchev, Damyan Vangelov, Vancho Donev, Georgi Nikolov, Maria Nikolova   +6 more
doaj   +1 more source

Laboratory surveillance of communicable diseases : enteric pathogens [PDF]

, 2007
Laboratories represent a crucial link in the surveillance chain. Since only a small proportion of cases of enteric infections are asked to submit a stool sample, one needs to assess the practices for testing for enteric pathogens and their notification ...
Gauci, Charmaine, Gilles, Herbert M., Mamo, Julian, O’Brien, Sarah J.   +3 more
core  

Allergic Disorders in Africa and Africans: Is it Primarily a Priority? [PDF]

, 2010
In Africa, the burden of some diseases has been a problem for centuries. The spectrum of African diseases includes allergies, infections, nutritional deficiencies, and natural disasters.
Adams, Araujo, Araujo, Asmah, Breman, Brugman, Butler, Carvalho, Chaisson, Cooper, Cooper, Cooper, Cullinan, Dagoye, Dagoye, Du Toit, Erasto Vitus Mbugi, Estmbale, Gadermaier, Grant, Jaffu Othniel Chilongola, Jeannin, Jeebhay, Jeebhay, Kamradt, Linneberg, Linneberg, Lopata, Lynch, Lynch, Madsen, Marshall, Matricardi, Matricardi, Mercer, Modjarrad, Moore, Motala, Ndiaye, Nicolaou, Nyan, Obeng, Obihara, Obihara, Obihara, Obihara, Obihara, Obihara, Okano, Pacifico, Palyvos, Pawankar, Platts-Mills, Potter, Potter, Potter, Potter, Rauter, Riedler, Scrivener, Sibanda, Sibanda, Steinman, Thyssen, Tohon, van den Biggelaar, van den Biggelaar, van den Biggelaar, van der Kleij, van Niekerk, Van Niekerk, Veien, Veien, Vergara, Weinberg, Westritschnig, Wuthrich, Yazdanbakhsh, Yazdanbakhsh, Yazdanbakhsh, Zar   +80 more
core   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

Advanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia, Xiaoyuan Jing, Ruoxi Wang, Mengke Su, Pei Wang, Yingxin Feng, Xiaohu Ren, Longfang Tu, Ping Wei, Zhen Lu, Yicong Jia, Feng Hong, Zhizhun Mo, Jiemeng Zou, Kang Huang, Caiyun Yan, Qianhui Zou, Liang Wang, Guoping Zhong, Zhi Zeng, Qiuliyang Yu, Wen Su, Xifei Yang, Fan Pan, Jianzhi Wang, Liping Wang, Lijun Kang, Paul J. Kenny, Zuxin Chen, Xin‐an Liu   +29 more
wiley   +1 more source

One Health: parasites and beyond [PDF]

, 2016
The field of parasitism is broad, encompassing relationships between organisms where one benefits at the expense of another. Traditionally the discipline focuses on eukaryotes, with the study of bacteria and viruses complementary but distinct ...
Chalmers, DAMER P. BLAKE, Fernandez Martin, Holland, Hosein, Johansen, Jones, Kahn, Kingsley, Leger, MARTHA BETSON, Mitchell, Rushton, Schwabe   +13 more
core   +3 more sources

Parasites and Infectious Diseases: Discovery by Serendipity and Otherwise [PDF]

Emerging Infectious Diseases, 2008
The author of this book retells several of the famous stories of discovery in the field of vector-borne and parasitic diseases through the eyes of some of the most prominent researchers working in this field today. But Esch does not stop there—he goes on to connect these early stories with more recent watershed contributions as recounted through a ...
openaire   +3 more sources

An Apple Susceptibility‐Related LRR Receptor‐Like Kinase MdRLKT21 Activates Plant Immunity by Hijacking a Trans‐Kingdom Fungal microRNA‐Like RNA

Advanced Science, EarlyView.
The apple susceptibility‐related LRR‐RLK MdRLKT21 competitively binds to fungal sRNA effectors and subsequently activates defenses by salvaging the expression of MdRLKT1 and MdRLKT2 and thereby releasing the resistance protein MdRFP1. These findings provide new insights into the molecular mechanism by which plants counteract pathogen‐secreted sRNA ...
Mingliang Lei, Jian Zhang, Jie Wang, Chengyu Gao, Yanting He, Runze Tian, Hao Feng, Lili Huang   +7 more
wiley   +1 more source

Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome

Advanced Science, EarlyView.
This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado, Samuel Vicente‐Gil, Esther Morel, Pablo Jiménez‐Barrios, Rocío Simón, Pedro Perdiguero, Diana Martín, Marta Vargas‐Ramírez, Niels Lorenzen, Jacob Günther Schmidt, Carolina Tafalla   +10 more
wiley   +1 more source