Results 161 to 170 of about 292,148 (372)

Designs and Materials of Electrodes for Electrochemical Sensors

open access: yesChemElectroChem, EarlyView.
Nowadays, electrochemical sensors and biosensors play a crucial role in modern life. This work highlights the importance of electrode material selection and chip design in optimizing sensor performance. It provides a practical guide for choosing suitable materials and structural configurations tailored to specific sensing applications, aiming to ...
Pierre J. Obeid   +8 more
wiley   +1 more source

[Infectious and parasitic diseases in Brazil, 2010 to 2017: considerations for surveillanceEnfermedades infecciosas y parasitarias en Brasil de 2010 a 2017: aspectos para la vigilancia sanitaria]. [PDF]

open access: yesRev Panam Salud Publica, 2020
de Souza HP   +7 more
europepmc   +1 more source

LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION

open access: yesProblems of Infectious and Parasitic Diseases
Background: Lymphocytic choriomeningitis virus (LHMV) infection is a neglected rodent-borne zoonotic infection but it is found all over the world because of the cosmopolitan distribution of its reservoirs.
Teodora Gladnishka   +3 more
doaj   +1 more source

Discovery of an Atypical Arp2/3 Complex in Malaria Parasites Sheds New Light on Nuclear Actin

open access: yesCytoskeleton, EarlyView.
ABSTRACT The Arp2/3 complex is a key actin nucleator essential for cytoskeletal dynamics in eukaryotes. Previously believed absent in apicomplexan parasites, we recently identified an atypical Arp2/3 complex in malaria parasites consisting of five divergent subunits and a putative kinetochore‐associated factor.
Franziska Hentzschel   +2 more
wiley   +1 more source

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

open access: yesChemMedChem, EarlyView.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali   +7 more
wiley   +1 more source

Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]

open access: yes
In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles   +6 more
core  

Seroprevalence of five neglected parasitic diseases among immigrants accessing five infectious and tropical diseases units in Italy: a cross-sectional study.

open access: yesClinical Microbiology and Infection, 2017
Giulia Martelli   +26 more
semanticscholar   +1 more source

C1′‐Branched Acyclic Nucleoside Phosphonates as Inhibitors of Plasmodium Falciparum 6‐Oxopurine Phosphoribosyltransferase

open access: yesChemMedChem, EarlyView.
Novel C1'‐branched acyclic nucleoside phosphonates were synthesized. The compounds are inhibitors of Plasmodium falciparum and human 6‐oxopurine phosphoribosyltransferases with Ki values as low as 0.4 µM and 0.7 µM, respectively. A phosphonodiamidate prodrug exhibited IC50 = 4.3 µM against a drug‐sensitive strain of P.
Jan Frydrych   +11 more
wiley   +1 more source

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