Global estimates and projections of mortality by cause, 1970-2015 [PDF]
The authors report estimates and projections of deaths by cause for major world regions, based on data from country reports to the World Health Organization and regression models.
Bulatao, Rodolfo A. +1 more
core
A novel inhibitor against the Bromodomain Protein 1 of the malaria pathogen Plasmodium falciparum
ChemMedChem, Accepted Article.The rise of drug resistances in malaria necessitates the exploration of novel therapeutic strategies. Targeting epigenetic pathways could open new, promising treatment avenues. In this study, we focus on the essential Bromodomain Protein 1 (PfBDP1) of the malaria pathogen Plasmodium falciparum. Utilizing the pan‐selective bromodomain inhibitor MPM6, we
Marius Amann +10 more
wiley +1 more source
M2ANET: Mobile Malaria Attention Network for efficient classification of plasmodium parasites in blood cells [PDF]
arXivMalaria is a life-threatening infectious disease caused by Plasmodium parasites, which poses a significant public health challenge worldwide, particularly in tropical and subtropical regions. Timely and accurate detection of malaria parasites in blood cells is crucial for effective treatment and control of the disease.
arxiv
Using runs of homozygosity to detect genomic regions associated with susceptibility to infectious and metabolic diseases in dairy cows under intensive farming conditions [PDF]
arXiv, 2016 Runs of homozygosity (ROH) are contiguous stretches of homozygous genome which likely reflect transmission from common ances- tors and can be used to track the inheritance of haplotypes of interest. In the present paper, ROH were extracted from 50K SNPs and used to detect regions of the genome associated with susceptibility to diseases in a population ...
arxiv
The Importance of Uncooked Vegetables in the Spread of Parasites and Infectious Diseases [PDF]
The American Journal of the Medical Sciences, 1901 n ...
openaire +2 more sources
Climate, biodiversity, land use changes and zoonotic infectious diseases in Southeast Asia : O15 [PDF]
, 2014 Numerous parasitic and infectious diseases are emerging, re-emerging or causing recurrent outbreaks in Southeast-Asia, a hot spot of both infectious disease emergence and biodiversity at threat.
Morand, Serge
core
Clinical Pharmacology &Therapeutics, EarlyView.Artemisinin‐based combination therapy (ACT) is the first‐line therapy for uncomplicated falciparum malaria, but artemisinin resistance in Asia and now sub‐Saharan Africa is threatening our ability to control and eliminate malaria. Triple‐ACTs have emerged as a viable alternative treatment to combat declining ACT efficacy due to drug‐resistant malaria ...
Joel Tarning +2 more
wiley +1 more source
Predicting and controlling the dynamics of infectious diseases [PDF]
arXiv, 2015 This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent parameter that defines the spread of infection.
arxiv
Laboratory surveillance of communicable diseases : enteric pathogens [PDF]
, 2007 Laboratories represent a crucial link in the surveillance chain. Since only a small proportion of cases of enteric infections are asked to submit a stool sample, one needs to assess the practices for testing for enteric pathogens and their notification ...
Gauci, Charmaine +3 more
core
NONTUBERCULOUS MYCOBACTERIA - CURRENT RISK IN BULGARIA
Problems of Infectious and Parasitic DiseasesBackground: Nontuberculous mycobacteria (NTM) are generally free-living and have a potential to cause opportunistic infection. More than 190 species of NTM have been identified (http://www.bacterio.net/mycobacterium.html), up to 60 species of them are ...
Yuliana Atanasova +3 more
doaj +1 more source