Results 61 to 70 of about 254,442 (298)

Integration of In Silico and In Vitro ADMET properties in lead identification and optimization of compounds for the treatment of parasitic diseases [PDF]

, 2012
Parasitic infections are the major causes of illness and death in tropical regions especially in Africa. The main parasitic diseases include leishmaniasis, filariasis, malaria, river blindness, Chagas disease and schistosomiasis.
Thelingwani, Roslyn
core   +1 more source

FERROPTOSIS IN CD4+ AND CD8+ T-CELLS IN THE SETTINGS OF HIV INFECTION

Problems of Infectious and Parasitic Diseases
Introduction: Elevation of intracellular iron concentration triggers ferroptosis. Understanding the regulation and pathophysiological mechanisms of this process in HIV infection may contribute to antiretroviral therapy (cART) monitoring.
Radoslava Emilova, Yana Todorova, Milena Aleksova, Reneta Dimitrova, Lyubomira Grigorova, Damian Vangelov, Ivaylo Alexiev, Nina Yancheva, Maria Nikolova   +8 more
doaj   +1 more source

A CASE OF VIBRIO VULNIFICUS INFECTION IN A DIABETES PATIENT WITH FATAL OUTCOME

Problems of Infectious and Parasitic Diseases, 2020
Aim. The aim of this report is to present the case of a 44-year-old male tourist from Belgium with type 1 diabetes who developed necrotizing fasciitis and sepsis caused by Vibrio vulnificus during his stay at the Bulgarian Black Sea Coast.
Maria Pavlova, K Tsankova, Rumiana Nenova, Iskra Tomova, V Velev, S Shishkov, Todor Kantardjiev   +6 more
doaj   +1 more source

Paleopathology of a putative colossosaurian caudal vertebra (Neosauropoda: Titanosauria) from the Presidente Prudente Formation, Brazil

The Anatomical Record, EarlyView.
Abstract Studies investigating paleopathologies in sauropods remain scarce despite their relative abundance in the fossil record. In this study we report new occurrence of paleopathological features, corresponding to a neoplasm found in a middle caudal vertebra (MCT.R.2120) of an advanced titanosaur from the Presidente Prudente Formation (Bauru Basin ...
Maria Luiza Peres Bertolossi, Kamila L. N. Bandeira, Roberta Veronese do Amaral, Arthur S. Brum, Rafael C. da Silva, Valéria Gallo   +5 more
wiley   +1 more source

HDAC inhibitors in parasitic diseases

, 2011
Parasitic diseases cause significant global morbidity and mortality, particularly in underdeveloped regions of the world. Malaria alone causes ~800 000 deaths each year, with children and pregnant women being at highest risk. There is no licensed vaccine
Ashraful Haque, Malcolm K Jones, Katherine T Andrews, Haque, Ashraful, Jones, Malcolm K, Andrews, Katherine T., Andrews, Katherine T, Jones, Malcolm K.   +7 more
core   +1 more source

Investigating the Heat Stability and Inactivation Conditions of Decapod Iridescent Virus 1 (DIV1)

Animal Research and One Health, EarlyView.
Heat treatment effectively inactivates decapod iridescent virus 1 (DIV1) under milder conditions than current WOAH recommendations. DIV1 infectivity was eliminated at 56°C for 30 min, 60°C for 15 min, or 70°C for 1 min, providing optimized heat treatment strategies for aquaculture biosecurity and seafood safety.
Yonghui Feng, Xiaomeng Guo, Jingyi Xing, Liang Qiu, Jie Huang   +4 more
wiley   +1 more source

TRACKING TWO-WAY HUMAN-MINK TRANSMISSION DURING AN OUTBREAK OF SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 ON A FARM IN BULGARIA

Problems of Infectious and Parasitic Diseases
Introduction: During the COVID-19 pandemic, it was observed that SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) can be transmitted from humans to various animals.
Ivelina Tifonova, Lyudmila Lazarova , Simona Tchakarova, Dean Donchev , Ivan Stoikov , Lyubomira Grigorova , Ivan Ivanov, Ivailo Alexiev , Neli Korsun , Iva Christova   +9 more
doaj   +1 more source

Mortality from infectious and parasitic diseases in selected countries of Latin America at the turn of the millennium [PDF]

, 2017
Mortality from infectious and parasitic diseases in selected countries of Latin America at the turn of the millennium Abstract This thesis deals with a group of causes of death called Certain Infectious and Parasitic Diseases defined by The International
Šorelová, Michaela
core  

Multivariate Analysis of Hematological Stress Biomarkers and Welfare Domains in Organic and Intensive Pig Farming in Italy: A Pilot Study

Animal Research and One Health, EarlyView.
Intensive or organic farming systems may expose pigs to management or environmental challenges. Our preliminary results concluded that organic farming might enhance adaptive immune function, showing that improvements in welfare can translate into measurable immunological benefits, based on the correlation between welfare assessment and physiological ...
Dorotea Ippolito, Talal Hassan, Antonio Marco Maisano, Stefania Bergagna, Cecilia Guasco, Barbara Miniscalco, Martina Tarantola, Elena Colombino, Claudio Caruso, Ahsan Muhammad, Silvia Mioletti, Laura Tomassone, Massimiliano Tursi, Cristina Vercelli, Giovanni Loris Alborali, Maria Teresa Capucchio   +15 more
wiley   +1 more source

SALIVARY SPECIFIC IgE TO D1 AND G6 IN PATIENTS WITH RHINITIS WITH OR WITHOUT S. AUREUS COLONIZATION

Problems of Infectious and Parasitic Diseases
Globally, allergic rhinitis impacts roughly 25% of children and 40% of adults. Immunoglobulin E (IgE) plays a crucial part in allergic inflammation, with two sources: spontaneously produced IgE, and IgE stemming from reactions to environmental allergens.
Diana Hristova, Antoaneta Decheva, Deyan Donchev, Damyan Vangelov, Vancho Donev, Georgi Nikolov, Maria Nikolova   +6 more
doaj   +1 more source