Results 161 to 170 of about 6,644,019 (302)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

APEC and Infectious Disease : Meeting the Challenge [PDF]

This paper considers how the Asia Pacific Economic Cooperation (APEC) process, given its institutional characteristics, can contribute to the efforts undertaken by the World Health Organisation (WHO) against infectious disease (ID).
Joel Gilbourd
core  

A Software Platform for Collaborative Infectious Disease Modeling. [PDF]

Nat Health
Consortium of Infectious Disease Modeling Hubs, Kerr M, Borchering R, Rivadeneira AC, Contamin L, Funk S, Hochheiser H, Howerton E, Krystalli A, Shandross L, Reich NG.   +10 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Compartment Model for Controlling Infectious Livestock Disease: Cost-Effective Control Strategies for Johne's Disease In Dairy Herds [PDF]

Replaced with revised version of paper 06/08/11.animal compartment model, dairy cattle disease, Johne’s disease, livestock disease control, Mycobacterium avium subspecies paratuberculosis, Farm Management, Livestock Production/Industries,
Grohn, Yrjo T., Tauer, Loren W., Schukken, Ynte H., Cho, Jaesung, Lu, Zhao, Smith, Rebecca L.   +5 more
core  

Infectious disease outcomes of NASA's health stabilization program. [PDF]

NPJ Microgravity
Blue RS, Mulcahy RA, Kreykes AJ, Haddon R, Pattarini JM, Johansen BD, Suresh R.   +6 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Development and Clinical Evaluation of an LC-MS/MS Method for the Determination of Isoniazid in Cerebrospinal Fluid from Tuberculous Meningitis

Infection and Drug Resistance
Mingming Xin,1,* Jiabin Liang,2,* Minggui Lin,1 Xiaohui Wang,1 Wenjing Hou,1 Leping Zhong,1 Xuzhu Ma,1 Xiwei Ji2 1Department of Infectious Diseases, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine ...
Xin M, Liang J, Lin M, Wang X, Hou W, Zhong L, Ma X, Ji X   +7 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Nationwide characteristics of infectious disease patients transported by helicopter ambulance in Türkiye. [PDF]

Turk J Med Sci
Bekgöz AG, Bilmez KD, Deniz MS.
europepmc   +1 more source