Results 151 to 160 of about 6,644,019 (302)

Infectious diseases snaphot 2008 [PDF]

open access: yes
The axis of CDC's efforts toward prevention, detection, and control of infectious diseases is the Coordinating Center for Infectious Diseases. CCID comprises four national centers with unique and complementary missions and capacities.

core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Health inequalities in infectious disease modelling. [PDF]

open access: yesCommun Health
Eggo RM, Robert A, Khunti K, Clapham HE.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Meeting of the Board of Scientific Counselors, Office of Infectious Diseases: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center, Atlanta, Georgia: May 3-4, 2017 [PDF]

open access: yes
A one-and-a-half day, open public meeting of the Board of Scientific Counselors (BSC), Office of Infectious Diseases (OID), was held on May 3-4, 2017, at the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia.

core  

Optimizing infectious disease mitigation under dynamic conditions. [PDF]

open access: yesProc Natl Acad Sci U S A
Müller L   +4 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Better infectious disease diagnostics is crucial to tackling antimicrobial resistance. [PDF]

open access: yesLancet Reg Health Am
Abreu A   +5 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

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