Results 131 to 140 of about 7,009,349 (302)

Nanomedicine for Infectious Diseases [PDF]

open access: yesNanomedicine, 2020
Harald Unterweger   +6 more
openaire   +2 more sources

Crisis and Emergency Risk Communication in an infectious disease outbreak

open access: yes
Crisis and Emergency Risk Communication in an infectious disease outbreak.CS2922228-APublication date from document properties.CERC_Infectious_Diseases_FactSheet ...

core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Efficacy and Safety of Contezolid as an Alternative to Linezolid for Treating MRSA Spinal Infections Following Linezolid-Induced Thrombocytopenia: A Single-Center Retrospective Study

open access: yesInfection and Drug Resistance
Xiucui Zhang,* Jianrong Wang,* Xinghao Cao, Shijie Wang, Junxue Wang, Huili Huang, Bo Wei Department of Infectious Diseases, Second Affiliated Hospital of Naval Medical University, Shanghai, People’s Republic of China*These ...
Zhang X   +6 more
doaj  

Influenza coinfection inhibits control of mycobacterial infection in a human challenge model

open access: yesNature Communications
Mycobacterium tuberculosis infection is a dynamic continuum. Clinical outcomes reflect complex host-pathogen interactions. Epidemiological and animal studies have suggested influenza coinfection as a risk factor for progression from contained infection ...
Claire M. Broderick   +15 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Climate change and infectious disease risk management: a localised health security perspective [PDF]

open access: yes, 2008
Pathogenic risks in relation to climate change are not fully understood and to a large extent have to be regarded as unpredictable. It is therefore important to focus attention on human vulnerability and coping for which more certain influences on ...
Collins, Andrew
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Application of a Machine Learning-Based Classification Approach for Developing Host Protein Diagnostic Models for Infectious Disease

open access: yes
In recent years, infectious disease diagnosis has increasingly turned to host-centered approaches as a complement to pathogen-directed ones. The former, however, typically requires the interpretation of complex multiple biomarker datasets to arrive at an
Thomas F. Scherr   +5 more
core   +1 more source

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