Results 121 to 130 of about 2,346,296 (295)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Nursing Clinics of North America, 2019 Emerging infectious diseases (EID) and reemerging infectious diseases are increasing globally. Zoonotic diseases are transmitted from animals to humans through direct contact or through food, water, and the environment. Vector-borne diseases are major sources of mortality and morbidity globally.
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Indonesian Journal of Tropical and Infectious Disease, 2019 IJTID Indonesian Journal of Tropical and Infectious Disease
doaj +1 more source
International Medical Case Reports JournalZhaxi Yangzong,1,* Xiying Gui,1,* Qingping Wen,1,* Hua Qian,1 Li Shi,1 Xinchao Liu1,2 1Department of Infectious Disease, Tibet Autonomous Region People’s Hospital, Lhasa, People’s Republic of China; 2Department of Infectious ...
Yangzong Z +5 more
doaj
THE ECONOMICS OF MANAGING WILDLIFE DISEASE [PDF]
The spread of infectious disease among and between wild domesticated animals has become a major problem worldwide. Upon analyzing the dynamics of wildlife growth and infection when the disease animals cannot be identified separately from healthy wildlife
Horan, Richard D., Wolf, Christopher A.
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Economic Analysis of Johne's Disease Control Strategies in Dairy Herds [PDF]
Infectious diseases play a critical role in determining the profitability of individual farms and maintaining the viability of livestock industries, international trade, and trade policies.
Cho, Jaesung +5 more
core +1 more source