Results 61 to 70 of about 2,044,342 (365)
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Data-driven approaches for predicting spread of infectious diseases through DINNs: Disease Informed Neural Networks [PDF]
arXiv, 2021 In this work, we present an approach called Disease Informed Neural Networks (DINNs) that can be employed to effectively predict the spread of infectious diseases. This approach builds on a successful physics informed neural network approaches that have been applied to a variety of applications that can be modeled by linear and non-linear ordinary and ...
arxiv
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
npj Vaccines, 2023 Synthetic biology has allowed for the industrial production of supply-limited sesquiterpenoids such as the antimalarial drug artemisinin and β-farnesene. One of the only unmodified animal products used in medicine is squalene, a triterpenoid derived from
Karl J. Fisher +17 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
NetworkFleming Symposium: Update on Quality, Patient Safety and Wellness [PDF]
, 2019 Objective: Examine how provider wellness is foundational to providing high-quality and safe ...
McCambridge, Matthew M, MD, MS, FACP, FCCP
core +1 more source
Infectious Diseases and Prematurity [PDF]
Infectious Diseases in Obstetrics and Gynecology, 2010 Researchers and clinicians have for several decades focused epidemiologic, basic biomedical and clinical investigation on preterm birth, low birth weight, and numerous sequelae of untimely birth. As the problem has been examined from the expertise of various specialists and from separate but at times overlapping disciplines, different etiologic ...
Bryan Larsen +4 more
openaire +3 more sources
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Behind the Scenes of “To Err Is Human” [PDF]
, 2019 Objective: Illustrate how public awareness of medical errors can improve patient ...
Eisenberg, Mike
core +1 more source