Results 61 to 70 of about 1,510,744 (256)
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Objective: To investigate the short-term efficacy and safety of different chemotherapy regimens combined with thalidomide, in the treatment of low-income patients with newly diagnosed HIV-associated diffuse large B-cell lymphoma. Methods: A retrospective
Peng fei Tao +7 more
doaj +1 more source
ハンタウイルスとは,ブニヤウイルス科ハンタウイルス属に含まれる一群のウイルスを指す総称である.その名は1973年李たちによって分離されたハンターンウイルスに由来する.ヒトに腎症候性出血熱(HFRS)やハンタウイルス肺症候群(HPS)など劇症の感染症をおこすウイルスが含まれる.ハンタウイルスの自然宿主は齧歯類であり,感染個体由来の乾燥した排泄物のエアゾールを介してヒトにも感染する.
openaire +2 more sources
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
In this chapter, we consider whether individual differences might play role in how a behavioral immune system operates and what that implies for human personality. We first highlight the theoretical reasons to expect variation in pathogen management mechanisms and the psychological models relevant to these mechanisms (e.g., behavioral immune system ...
Ackerman , Joshua +2 more
openaire +2 more sources
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Indonesian Journal of Tropical and Infectious Disease
doaj +1 more source

