Results 151 to 160 of about 285,146 (304)

Multi‐Omics Profiling of High‐Grade Serous Ovarian Cancer Reveals an Inflammation‐Related Lipid Metabolism Subtype Associated With Platinum Resistance

Advanced Science, EarlyView.
Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao, Junyi Li, Bo Zheng, Wanshan Liu, Yaru Wang, Shufeng Wang, Ying Cui, Huiqin Guo, Hongxia Wang, Ting Xiao, Kun Qian, Jing Zuo   +11 more
wiley   +1 more source

Information-guided adaptive learning approach for active surveillance of infectious diseases [PDF]

The infectious disease surveillance system is a key support tool for public health decision making. Current research concentrates on optimizing static sentinel deployment to address the problem of incomplete data due to the lack of sufficient ...
Zhang, Chenyang, Wang, Ruiqi, Zhou, Lian, Shi, Benyun, Du, Zhanwei, Tan, Qi, Xia, Jiwen   +6 more
core   +1 more source

Influenza vaccine effectiveness in school outbreaks during a A(H3N2) subclade K (J.2.4.1)-dominated season in Beijing, China, 2025-26

International Journal of Infectious Diseases
: Objectives: Schools are high-risk settings for influenza transmission. During the 2025-26 Northern Hemisphere season, influenza A(H3N2) subclade K (J.2.4.1) rapidly emerged and became predominant, but vaccine effectiveness (VE) in school-associated ...
Ying Shen, Chunna Ma, Daitao Zhang, Weixian Shi, Wei Duan, Jia Li, Lu Zhang, Dan Wu, Jiaojiao Zhang, Jiaxin Ma, Yingying Wang, Xiaodi Hu, Shuning Yan, Yuanzhi Di, Jiachen Zhao, Hui Xu, Guilan Lu, Yimeng Liu, Quanyi Wang, Peng Yang, Zhaomin Feng   +20 more
doaj   +1 more source

Surveillance, Prevention Fight Infectious Disease

American Journal of Veterinary Research, 2023
Ying, Fang, Weiping, Zhang, Bob, Rowland, Peter, Constable   +3 more
openaire   +2 more sources

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Unexplained death surveillance in Minnesota [PDF]

This exciting session of Grand Rounds focuses on rapid identification of emerging infectious diseases. As our world increases in interconnectivity of both technology and people, the rapid identification of emerging infectious diseases becomes more ...
Centers for Disease Control and Prevention (U.S.) Office of the Associate Director for Communication.
core  

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Changing dynamics of bloodstream infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium in Germany, 2017–2023: a continued burden of disease approach

Antimicrobial Resistance and Infection Control
Background Antimicrobial resistance is a global threat to public health, with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREfm) being major contributors.
Simon Brinkwirth, Marcel Feig, Ines Noll, Tim Eckmanns, Achim Dörre, Sebastian Haller, Niklas Willrich   +6 more
doaj   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Erratum to: Comparative evaluation of the diagnosis, reporting and investigation of malaria cases in China, 2005–2014: transition from control to elimination for the national malaria programme

Infectious Diseases of Poverty, 2017
Jun-Ling Sun, Sheng Zhou, Qi-Bin Geng, Qian Zhang, Zi-Ke Zhang, Can-Jun Zheng, Wen-Biao Hu, Archie C.A. Clements, Sheng-Jie Lai, Zhong-Jie Li   +9 more
doaj   +1 more source