Results 141 to 150 of about 5,837,960 (266)

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

Advanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang, Lili Zhi, Tian Huang, Lingya Feng, Chaoqun Chen, Huanhuan Wei, Xiaolong Liu, Lei Chen, Jinrui Zhang, Ge Zhang, Baofeng Zhao, Rong Liu, Dan Chen, Yangfan Qi, Yang Wang   +14 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 2 2004

, 2004
GP consultation rates for influenza-like illness in Ireland increased further during week 2, with 5 influenza A positive detections. The WHO has confirmed the presence of avian influenza virus H5N1 in three patients who died of severe respiratory ...
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source

Weekly Influenza Surveillance Report Week 13

, 2001
The GP consultation rate for week 12, week ending the 25th of March, has been updated to 53 cases per 100,000 population, following receipt of reports from 17 sentinel general practices.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Transport–Reaction–Signal Coupling in Lateral Flow Assays for Next‐Generation Point‐of‐Care Diagnostics

Advanced Science, EarlyView.
Lateral flow assays are evolving into interdisciplinary, system‐level sensing platforms. Recent innovations are deconstructed through coupled phases of mass transfer, reaction, and signal transduction, revealing interdependence across porous materials, interfacial chemistry, nanolabels, readout devices, and data‐enabled analysis.
Yan Pan, Yuewei Li, Chao Mi, Zhengwen Yang, Lana McClements, Steven J. Langford, Jiayan Liao   +6 more
wiley   +1 more source

Utilizing rapid diagnostic tests in infectious disease surveillance and response in humanitarian emergencies. [PDF]

Front Public Health
Herilla ME, Townes DA, Boyd AT.
europepmc   +1 more source

Weekly Influenza Surveillance Report Week 17

, 2001
During week 17, week ending the 29th of April, influenza activity has continued to decrease. There were 6 cases of influenza-like illness reported from sentinel general practices.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core  

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Community-led standards for global wastewater-based infectious disease surveillance. [PDF]

PLOS Glob Public Health
Smith EA, Ahmadi Jeshvaghane M, Pilz DA, Shitindo M, Costa da Silva J, Gable L, Brown K, Calvert-Joshua T, Diedericks F, Ünal G, Paull JS, Shukla NB, Muhammad Z, Amofa JO, Liu EJ, Griffiths EJ, Landgraff C, Guerfali FZ, Tiffin N, Levy JI, Public Health Alliance for Genomic Epidemiology (PHA4GE) Wastewater Surveillance Working Group.   +20 more
europepmc   +1 more source

Weekly Influenza Surveillance Report Week 45 2002

, 2002
The sentinel GP consultation rate for influenza-like illness continues to remain at low levels. There have been no positive detections of influenza virus this season.
National Disease Surveillance Centre (NDSC), National Virus Reference Laboratory (NVRL), Irish College of General Practitioners (ICGP)   +2 more
core