Results 191 to 200 of about 5,837,960 (266)

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

UTILIZING A CAPTURE-RECAPTURE STRATEGY TO ACCELERATE INFECTIOUS DISEASE SURVEILLANCE. [PDF]

Ann Appl Stat
Ge L, Zhang Y, Waller L, Lyles R.
europepmc   +1 more source

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

[Airport and Port Wastewater-based Infectious Disease Surveillance]. [PDF]

Jugan Geongang Gwa Jilbyeong
Lee DI, Kim SH, Kim OS.
europepmc   +1 more source

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo, Jinyin Yan, Wenli Li, Jin Wang, Lu Liu, Chengmei Zhang, Wei Cao, Shanshan Yao, Haibo Gong, Yi He, Zihan Zhou, Siyan Chen, Li Feng, Haijing Deng   +13 more
wiley   +1 more source

Surveillance System for Infectious Disease Prevention and Management: Direction of Korea's Infectious Disease Surveillance System. [PDF]

J Korean Med Sci
Jang Y, Lee H, Park H.
europepmc   +1 more source

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

Annals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini, Sean J. Pittock, Laura Cacciaguerra, Howard L. Weiner, Luke A. Schwerdtfeger   +4 more
wiley   +1 more source

Embedding risk monitoring in infectious disease surveillance for timely and effective outbreak prevention and control. [PDF]

BMJ Glob Health
Ingelbeen B, van Kleef E, Mbala P, Danis K, Macicame I, Hens N, Cleynen E, van der Sande MAB.   +7 more
europepmc   +1 more source

State-space modelling for infectious disease surveillance data: Stochastic simulation techniques and structural change detection. [PDF]

Infect Dis Model
Prashad CD.
europepmc   +1 more source

Advances in whole genome sequencing for foodborne pathogens: implications for clinical infectious disease surveillance and public health. [PDF]

Front Cell Infect Microbiol
Gomes E, Araújo D, Nogueira T, Oliveira R, Silva S, Oliveira LVN, Azevedo NF, Almeida C, Castro J.   +8 more
europepmc   +1 more source