Results 151 to 160 of about 159,179 (308)

Pharmacokinetic Adaptations in Pregnancy: Implications for Optimizing Antiretroviral Therapy in HIV-Positive Women

Pharmaceutics
Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women.
Natalia Briceño-Patiño, María Camila Prieto, Paula Manrique, Carlos-Alberto Calderon-Ospina, Leonardo Gómez   +4 more
doaj   +1 more source

SMart Nanoparticle–Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing

Advanced Science, EarlyView.
The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

Mathematical modeling of the spread of the coronavirus under strict social restrictions

Mathematical Methods in the Applied Sciences, EarlyView., 2021
We formulate a simple susceptible‐infectious‐recovery (SIR) model to describe the spread of the coronavirus under strict social restrictions. The transmission rate in this model is exponentially decreasing with time. We find a formula for basic reproduction function and estimate the maximum number of daily infected individuals.
Mo'tassem Al‐arydah, Hailay Berhe, Khalid Dib, Kalyanasundaram Madhu   +3 more
wiley   +1 more source

Understanding HIV/AIDS in the African Context

, 2018
This book of readings is intended for courses in Global Health. The editors asked Prof. Stillwaggon to contribute a chapter summarizing her years of work on the spread of HIV/AIDS in populations among whom bacterial, fungal, parasitic, and viral diseases
Sawers, Larry, Stillwaggon, Eileen
core  

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

Advanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Integrated Ultrasound Device for Precision Bladder Volume Monitoring via Acoustic Focusing and Machine Learning

Advanced Science, EarlyView.
We present a conformable wearable ultrasound patch for noninvasive bladder volume monitoring. A flexible PZT array combined with a concave acoustic lens concentrates acoustic energy and improves depth selectivity through the anterior pelvic wall.
Long Long Cao, Feng Wen Wang, Jingwei Xue, Fulei Liu, Ming Liang Jin   +4 more
wiley   +1 more source

An optimized strategy triggered at the 2nd immunization visit to prevent HIV acquisition by breastfeeding: a phase 2 trial in Burkina Faso (PREVENIR-PEV)

BMC Infectious Diseases
Background Mother-to-child transmission of HIV during breastfeeding remains a challenge in low- and middle-income countries (LMIC). A prevention package was initiated during the highly attended 2nd visit of the Expanded Program of Immunisation (EPI-2) to
Anaïs Mennecier, Béninwendé Leticia Delphine Sakana, Morgana D’Ottavi, Souleymane Tassembedo, Jean-Pierre Moles, Dramane Kania, Ajani Ousmane Taofiki, Franck Edgar Kadeba, Ibrahima Diallo, Sabrina Eymard-Duvernay, Nicolas Meda, Beatriz Mosqueira, Paulin Fao, Nicolas Nagot, for the PREVENIR-PEV Study Group, Philippe Vande Perre   +15 more
doaj   +1 more source