Results 191 to 200 of about 735,761 (286)

Homophily and social mixing in a small community: Implications for infectious disease transmission. [PDF]

PLoS One
Pasquale DK, Welsh W, Bentley-Edwards KL, Olson A, Wellons MC, Moody J.   +5 more
europepmc   +1 more source

High connectivity and human movement limits the impact of travel time on infectious disease transmission

, 2023
John RS, Miller JC, Muylaert RL, Hayman DTS.   +3 more
europepmc   +1 more source

Implications of a travel connectivity-based approach for infectious disease transmission risks in Oceania. [PDF]

BMJ Open, 2021
Cadavid Restrepo A, Furuya-Kanamori L, Mayfield H, Nilles E, Lau CL.   +4 more
europepmc   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source

Pairwise Accelerated Failure Time Regression Models for Infectious Disease Transmission in Close-Contact Groups With External Sources of Infection. [PDF]

Stat Med
Sharker Y, Diallo Z, KhudaBukhsh WR, Kenah E.   +3 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

The cow GUTBIOME CY study: investigating the composition of the cattle gut microbiome in health and infectious disease transmission in cyprus. [PDF]

BMC Vet Res
Mavrides DE, Liapi M, Ierodiakonou D, Pipis C, Malas S, Gentekaki E, Tsaousis AD.   +6 more
europepmc   +1 more source

Regional Relative Risk, a Physics-Based Metric for Characterizing Airborne Infectious Disease Transmission. [PDF]

Appl Environ Microbiol, 2021
Dillon MB, Dillon CF.
europepmc   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Human mobility and the infectious disease transmission: A systematic review. [PDF]

Geo Spat Inf Sci
Lessani MN, Li Z, Jing F, Qiao S, Zhang J, Olatosi B, Li X.   +6 more
europepmc   +1 more source