Results 51 to 60 of about 416,582 (301)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

The impact of economic crises on communicable disease transmission and control: a systematic review of the evidence.

PLoS ONE, 2011
There is concern among public health professionals that the current economic downturn, initiated by the financial crisis that started in 2007, could precipitate the transmission of infectious diseases while also limiting capacity for control.
Marc Suhrcke, David Stuckler, Jonathan E Suk, Monica Desai, Michaela Senek, Martin McKee, Svetla Tsolova, Sanjay Basu, Ibrahim Abubakar, Paul Hunter, Boika Rechel, Jan C Semenza   +11 more
doaj   +1 more source

When more transmission equals less disease: reconciling the disconnect between disease hotspots and parasite transmission. [PDF]

PLoS ONE, 2013
The assumed straightforward connection between transmission intensity and disease occurrence impacts surveillance and control efforts along with statistical methodology, including parameter inference and niche modeling.
Andrew W Park, Krisztian Magori, Brad A White, David E Stallknecht   +3 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Neonatal outcomes among pregnant women with COVID-19: a systematic scoping review and meta-analysis

BMC Pregnancy and Childbirth
Background Current findings on the neonatal outcomes among pregnant women infected with COVID-19 remain inconclusive. The purpose of this systematic scoping review and meta-analysis was to summarize the literature regarding this topic and provide an ...
Yongqiu Li, Ying Lu, Huilin Tang, Eliot A. Spector, Xiaoxiao Wen, Kimberly Germinal, Alexandra Milfort, Yi Guo, Sarah Bost, Elizabeth Shenkman, Jiang Bian, Hui Hu, Jingchuan Guo   +12 more
doaj   +1 more source

Fractional Dynamics of Infectious Disease Transmission with Optimal Control [PDF]

Mathematics Interdisciplinary Research
This article investigates and studies the dynamics of infectious disease transmission using a fractional mathematical model based on Caputo fractional derivatives‎.
Reza Akbari, Leader Navaei
doaj   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Exploring the impact and transmission of Salmonella Dublin in crossbred dairy calves

Journal of Dairy Science
: Salmonella enterica serotype Dublin (S. Dublin) is an increasing concern within the dairy industry, particularly due to its effect on morbidity and mortality in young dairy calves.
Francesca Pharo, Rita Couto Serrenho, Amy L. Greer, Riley Oremush, Gregory Habing, Murray Gillies, Aaron Keunen, David L. Renaud   +7 more
doaj   +1 more source

Infectious Disease Modeling and the Dynamics of Transmission [PDF]

, 2007
The dynamics of any infectious disease are heavily dependent on the rate of transmission from infectious to susceptible hosts. In many disease models, this rate is captured in a single compound parameter, the probability of transmission P. However, closer examination reveals how beta can be further decomposed into a number of biologically relevant ...
Real, L. A., Biek, R.
openaire   +2 more sources