Results 61 to 70 of about 446,047 (253)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Phylogenetic analysis reveals a correlation between the expansion of very virulent infectious bursal disease virus and reassortment of its genome segment B [PDF]

, 2006
Infectious bursa] disease virus (IBDV) is a birnavirus causing immunosuppressive disease in chickens. Emergence of the very virulent form of IBDV (vvIBDV) in the late 1980s dramatically changed the epidemiology of the disease.
Lam, PY, Ng, PTW, Lam, TY, Lam, Tsan-Yuk, Rambaut, Andrew, Drummond, A, Zeng, F, Drummond, Alexei, Lee, Yiu-Fai, Yip, Chi-Wai, Leung, Frederick C. C., Rambaut, A, Zeng, Fanya, Hon, CC, Lam, Pui-Yi, Ng, Patrick T. W., Lee, YF, Hon, Chung-Chau, Yip, CW, Leung, FCC   +19 more
core   +1 more source

Research on an Infectious Disease Transmission by Flocking Birds [PDF]

The Scientific World Journal, 2013
The swarm intelligence is becoming a hot topic. The flocking of birds is a natural phenomenon, which is formed and organized without central or external controls for some benefits (e.g., reduction of energy consummation). However, the flocking also has some negative effects on the human, as the infectious disease H7N9 will easily be transmited from the
Tang, Mingsheng, Mao, Xinjun, Guessoum, Zahia   +2 more
openaire   +4 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source

Tuberculosis transmission attributable to close contacts and HIV status, Malawi. [PDF]

, 2006
We conducted the first molecular study of tuberculosis (TB) to estimate the role of household contact and transmission from HIV-positive putative source contacts (PSCs) in a high HIV-prevalence area.
Yates, Malcolm D, Traore, Hamidou, Judith R. Glynn, Hamidou Traore, Michael Mwenebabu, Fine, Paul E.M., Glynn, Judith R., Mwenebabu, M, Glynn, Judith R, Crampin, Amelia C, Mwenebabu, Michael, Mwaungulu, Lorren, Drobniewski, FD, Amelia C. Crampin, Mwaungulu, L, Sian Floyd, Fine, Paul EM, Traoré, H, Paul E.M. Fine, Crampin, Amelia C., Chaguluka, SD, Floyd, Sian, Yates, Malcolm D., Chaguluka, Steven D, Lorren Mwaungulu, Steven D. Chaguluka, Malcolm D. Yates, Drobniewski, Francis, Glynn, JR, Yates, MD, Crampin, AC, Chaguluka, Steven D., Francis Drobniewski, Fine, PEM, Floyd, S   +34 more
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic [PDF]

, 2004
This paper reviews current understanding of the epidemiology, transmission dynamics and control of the aetiological agent of severe acute respiratory syndrome (SARS).
Hedley, A, Leung, Gabriel M, Ghani, Azra C, Christophe Fraser, Lam, T, Anderson, RM, Ghani, AC, Lam, TH, Azra C. Ghani, Donnelly, C, Leung, GM, Fraser, C, Ferguson, Neil M, Fraser, Christophe, Donnelly, CA, Hedley, AJ, Christl A. Donnelly, Anderson, Roy M, Ferguson, NM, Riley, Steven, Roy M. Anderson, Leung, G, Hedley, Anthony J, Anthony J. Hedley, Ghani, A, Ferguson, N, Anderson, R, Donnelly, Christl A, Steven Riley, Riley, S, Neil M. Ferguson, Gabriel M. Leung, Tai H. Lam   +32 more
core   +1 more source

Infectious Disease in the Workplace: Quantifying Uncertainty in Transmission

Bulletin of Mathematical Biology
AbstractUnderstanding disease transmission in the workplace is essential for protecting workers. To model disease outbreaks, the small populations in many workplaces require that stochastic effects are considered, which results in higher uncertainty. The aim of this study was to quantify and interpret the uncertainty inherent in such circumstances. We
Hamley, Jonathan Ian Douglas, Beldi, Guido Jakob Friedrich, Sánchez Taltavull, Daniel   +2 more
openaire   +2 more sources

On the Role of Asymptomatic Infection in Transmission Dynamics of Infectious Diseases [PDF]

Bulletin of Mathematical Biology, 2007
We propose a compartmental disease transmission model with an asymptomatic (or subclinical) infective class to study the role of asymptomatic infection in the transmission dynamics of infectious diseases with asymptomatic infectives, e.g., influenza. Analytical results are obtained using the respective ratios of susceptible, exposed (incubating), and ...
Hsu, Sze-Bi, Hsieh, Ying-Hen
openaire   +3 more sources