Results 121 to 130 of about 2,133,431 (349)

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

open access: yesFEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Integrating socioeconomic and geographic data to enhance infectious disease prediction in Brazilian cities [PDF]

open access: yesarXiv
Supervised machine learning models and public surveillance data has been employed for infectious disease forecasting in many settings. These models leverage various data sources capturing drivers of disease spread, such as climate conditions or human behavior.
arxiv  

Infectious Diseases Institute [PDF]

open access: yes, 2017
IMPACT. 1: Provide infectious diseases communications and resources for the community, key stakeholders, and policy makers.OSU PARTNERS: College of Arts and Sciences; College of Dentistry; College of Education and Human Ecology; College of Engineering ...
Oglesbee, Mike
core  

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Interview: Radhika Polisetty

open access: yesEMJ Microbiology & Infectious Diseases, 2023
Radhika Polisetty
doaj   +1 more source

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