Results 111 to 120 of about 2,418,159 (299)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
West Nile Update – Preparing for Summer 2004
Canadian Paediatric Society Infectious Diseases and Immunization Committee
doaj +1 more source
Davide Dalu,1 Rosaria Iardino,2 Emanuela Vaccher,3 Angioletta Lasagna,4 Margherita Digaetano,5 Alberto Giovanni Leone,6 Lorenzo Ruggieri,1 Eva Massari,2 Eva Blondeaux,7 Andrea Gori,8,9 Cristina Mussini,10 Giuliano Rizzardini,9 Matteo Bassetti,11,12 ...
Dalu D +20 more
doaj
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
West Nile Virus - Mosquitoes No Longer Just an Annoyance!
Canadian Paediatric Society, Infectious Diseases and Immunization Committee
doaj +1 more source
Chenliang Fan,1 Xiaosi Li,1 Baizhi Pi,2 Jiasheng Wu,3 Heping Shen,3 Yumiao Guo,3 Xiaoyan Wu1 1Department of Laboratory Medicine, the Second Affiliated Hospital of Jiaxing University, Jiaxing, 314001, People’s Republic of China; 2Department of Intensive ...
Fan C +6 more
doaj
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
The Use of Antibiotic Therapy as an Adjunct in Treatment of Bone and Joint Infections
Canadian Paediatric Society, Infectious Diseases and Immunization Committee
doaj +1 more source
R S, Heyderman, E, Larson
openaire +2 more sources

