Results 121 to 130 of about 1,609,728 (258)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Phase I, Randomized, Double-Blind, Placebo-Controlled Trial Investigating the Safety, Tolerability, and Pharmacokinetics of BS1801 in Healthy Chinese Adult Subjects

open access: yesDrug Design, Development and Therapy
Guiling Chen,1,* Guoping Sheng,1,* Kaiqi Wu,1 Tinghan Jin,1 Qi Jiang,1 Tong Guo,1 Yifan Chen,2 Hanwei Yin,3 Guozhou Zhang,3 Zhenwei Shen,1 Huihui Zeng3 1Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren ...
Chen G   +10 more
doaj  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

A Case Report of Unusual Diagnosis of Melioidosis in a Non-Traveler: Implications for Transmission and Diagnosis

open access: yesInfection and Drug Resistance
Chenliang Fan,1 Xiaosi Li,1 Baizhi Pi,2 Jiasheng Wu,3 Heping Shen,3 Yumiao Guo,3 Xiaoyan Wu1 1Department of Laboratory Medicine, the Second Affiliated Hospital of Jiaxing University, Jiaxing, 314001, People’s Republic of China; 2Department of Intensive ...
Fan C   +6 more
doaj  

Editorial: Perspectives in clinical infectious diseases: 2024/2025. [PDF]

open access: yesFront Cell Infect Microbiol
Oliveira R   +3 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Editorial: Cell migration and tissue remodeling in infectious diseases. [PDF]

open access: yesFront Cell Infect Microbiol
de Menezes JPB   +2 more
europepmc   +1 more source

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