Results 51 to 60 of about 10,634,853 (332)

Notification of Infectious Diseases [PDF]

BMJ, 1887
n ...
Hy. Tomkins, E.M. Shirtliff
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19

Clinical Infectious Diseases, 2020
Background There are many pharmacologic therapies that are being used or considered for treatment of COVID-19. There is a need for frequently updated practice guidelines on their use, based on critical evaluation of rapidly emerging literature. Objective
A. Bhimraj, Rebecca L. Morgan, A. Shumaker, V. Lavergne, L. Baden, Vincent Chi-Chung  Cheng, Kathryn M. Edwards, R. Gandhi, William J Muller, J. O’Horo, S. Shoham, M. H. Murad, Reem A. Mustafa, S. Sultan, Y. Falck-Ytter   +14 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19:Serologic Testing

Clinical Infectious Diseases, 2020
Background The availability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic testing has rapidly increased. Current assays use a variety of technologies, measure different classes of immunoglobulin or immunoglobulin combinations ...
Kimberly E Hanson, A. M. Caliendo, Cesar A. Arias, Janet A Englund, Mary K. Hayden, Mark J. Lee, M. Loeb, Robin Patel, Osama Altayar, Abdallah El Alayli, S. Sultan, Y. Falck-Ytter, V. Lavergne, Rebecca L. Morgan, M. H. Murad, A. Bhimraj, Reem A. Mustafa   +16 more
semanticscholar   +1 more source

Infectious Diseases [PDF]

, 2019
Infectious disease is one of the most common causes of acute care visits to outpatient pediatric clinics, urgent care facilities, and hospital emergency departments.
openaire   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Increasing prevalence of extended-spectrum-betalactamase among Gram-negative bacilli in Latin America – 2008 update from the Study for Monitoring Antimicrobial Resistance Trends (SMART)

Brazilian Journal of Infectious Diseases, 2011
Objectives: This analysis of the Study for Monitoring Antimicrobial Resistance Trends (SMART) evaluated the susceptibility patterns of Enterobacteriaceae in Latin America in 2008, with emphasis on susceptibility trends of E. coli and K.
Maria Virginia Villegas, MD, MSc, Infectious Diseases, Manuel Guzmán Blanco, MD, Infectious Diseases, Jose Sifuentes-Osornio, MD, Infectious Diseases, Flávia Rossi, MD, PhD   +3 more
doaj  

The contribution of pre-symptomatic infection to the transmission dynamics of COVID-2019 [version 1; peer review: 2 approved]

Wellcome Open Research, 2020
Background: Pre-symptomatic transmission can be a key determinant of the effectiveness of containment and mitigation strategies for infectious diseases, particularly if interventions rely on syndromic case finding. For COVID-19, infections in the absence
Yang Liu, Centre for Mathematical Modelling of Infectious Diseases nCoV Working Group, Sebastian Funk, Stefan Flasche   +3 more
doaj   +1 more source