Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen+8 more
wiley +1 more source
Risk factors for endogenous endophthalmitis in infectious endocarditis patients. [PDF]
Shah MK+5 more
europepmc +1 more source
Poor long-term outcomes of intravenous drug users with infectious endocarditis. [PDF]
Caceres J+7 more
europepmc +1 more source
ABSTRACT Background The long‐term valve durability of supra‐annular self‐expanding valves (SEV) and intra‐annular balloon‐expandable valves (BEV) in patients with small aortic annuli remains unexplored. Aims This study aimed to determine the long‐term bioprosthetic valve durability with SEV versus BEV in patients with small aortic annuli.
Yutaka Matsuhiro+12 more
wiley +1 more source
Brief comment on "Mitral valve repair and replacement in infectious endocarditis: a systematic review and meta-analysis of clinical outcome". [PDF]
Moldon HJ, Ahmadi-Hadad A.
europepmc +1 more source
Successful treatment of infectious endocarditis-associated glomerulonephritis during active hepatitis C infection: a case report. [PDF]
Zito A+6 more
europepmc +1 more source
Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Presenting After the Initiation of Staphylococcus hominis Infectious Endocarditis Treatment: A Case Report and Updated Review of Management Considerations [PDF]
Khoa A. Nguyen, Mohammed Sohail Ahmed
openalex +1 more source
Brucella Pneumonia Mimicking Pulmonary Tuberculosis: A Case Report
ABSTRACT Brucellosis is a zoonotic infection prevalent in certain regions. It typically presents with nonspecific symptoms but can also cause focal organ involvement, including the musculoskeletal, neurological, or pulmonary systems. Herein, we present a case of a 31‐year‐old male patient who presented with a 5‐day history of fever and cough.
Ammar Chapra+5 more
wiley +1 more source
Objective: In patients who underwent mitral valve replacement for infectious endocarditis, we evaluated the association of prosthesis choice with readmission rates and causes (the primary outcomes), as well as with in-hospital mortality, cost, and length
Katie J. Hogan, BS+7 more
doaj