Results 131 to 140 of about 16,276 (211)

An Anatomist's View on the Crosstalk Between the Liver and the Lung

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
The liver and the lung have a similar three‐dimensional and cellular architecture as well as functional communalities. The structural, functional, and pathophysiological interplay between both organs suggests the existence of an interorgan axis, the liver‐lung axis. Created in biorender.com.
Tanja Kloock, Julia Schipke, Christian Mühlfeld   +2 more
wiley   +1 more source

Infectious spleen and kidney necrosis virus induces the reactive oxidative species/Nrf2-mediated oxidative stress response for the regulation of mitochondrion-mediated Bax/Bak cell death signals in GF-1 cells. [PDF]

Front Microbiol, 2022
Chen PH, Hsueh TC, Hong JR.
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

Stimuli‐Responsive Lipid‐Based Nanocarriers for Antimicrobial Therapy

Advanced Therapeutics, Volume 9, Issue 11, November 2026.
This manuscript demonstrated, through a scoping review of the literature, that modifying lipid nanocarriers with organic and inorganic excipients is a promising alternative to increase in vitro drug release of antimicrobial compounds under the studied stimulus and significantly enhance in vitro and in vivo antimicrobial activity compared to isolated ...
Brenda Maria Silva Bezerra, Adrian Lima Roberto, Luiz Gustavo Girão Lima, Mariana Rillo Sato, Leila Aparecida Chiavacci, João Augusto Oshiro‐Junior   +5 more
wiley   +1 more source

M11‐CAR T cells inhibit murine cytomegalovirus in vitro upon recognition of virion‐ and cell‐associated glycoprotein B

Clinical &Translational Immunology, Volume 15, Issue 11, 2026.
Abstract Objectives Viral infections are predominantly managed with conventional antiviral drugs, which, despite their efficacy, can cause toxicity and promote resistance. Cell‐based immunotherapies offer an alternative, but cytomegaloviruses (CMV) profoundly interfere with MHC class I antigen presentation, thereby impairing conventional virus‐specific
Sabrina Kübel, Christopher Garçon, Hanna Menschikowski, Arne Cordsmeier, Jens‐Christian Albrecht, Friederike Oltmanns, Larissa Bauer, Manuel Hermann, Kristina Holdt, Heinrich Sticht, Marco Thomas, Thomas H Winkler, Brigitte Scholz, Doris Jungnickl, Armin Ensser   +14 more
wiley   +1 more source

Incidence of Fish Pathogenic Viruses among Anadromous Salmonids in the Northern Part of Japan, 1976-1987 [PDF]

, 1991
During the period from September 1976 to December 1987, various species of mature salmonid fish, including masu (Oncorhynchus masou), chum (O. keta), pink (O. gorbuscha), kokanee salmon (O.
Yoshimizu, M., Kimura, T., Nomura, T., Awakura, T.   +3 more
core  

RNA‐Binding Protein NOVA1 Restrains Immune Escape and Liver Metastasis in Colorectal Cancer via Stabilizing NRXN1 mRNA

The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
The RNA‐binding protein neuro‐oncological ventral antigen 1 (NOVA1) is downregulated in colorectal cancer (CRC) and is associated with poor prognosis. NOVA1 binds and stabilizes neurexin 1 (NRXN1) messenger RNA (mRNA), thereby increasing NRXN1 expression and suppressing tumor cell proliferation, invasion, immune evasion, and liver metastasis; NRXN1 ...
ZhiXing Wei, Xing Wei, LinSai Cui, YaXin Pang, Guang Cui, Zhen Wei, ZhaoCai He, BuQiang Wu   +7 more
wiley   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

FGF13 Alleviates the Aging Process in Mice by Regulating Astrocyte Function in the Medial Prefrontal Cortex via Phafin2 Signaling Pathway

Aging Cell, Volume 25, Issue 11, November 2026.
FGF13 is significantly downregulated in the aging brain, particularly in cortical astrocytes within the medial prefrontal cortex. Genetic knockdown of FGF13 in astrocytes accelerates aging phenotypes and impairs neurological function in mice, while its overexpression effectively delays cognitive decline.
Rui Zheng, Zheng Tu, Yang Fang, Caixiang Zhuang, Yuchao Zhang, Yibo Ying, Zhiyi Feng, Ziyang Jin, Yanyan Zheng, Zhouguang Wang   +9 more
wiley   +1 more source

Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

British Journal of Pharmacology, Volume 183, Issue 21, Page 6329-6351, November 2026.
Abstract Background and Purpose Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA‐19a‐3p (miR‐19a‐3p), but the relevance of this axis in ARDS‐associated pulmonary fibrosis remains
Weilun Liu, Hsiaohsuan Wang, Hsuanfu Kuo, Chiahung Yen, Modasang Hua, Chiayuan Chang, Zhiwei Xu, Ifan Liu, Chongchao Hsieh, Chihhsin Hsu, Chiayang Li, Shuchi Wang, Yunghsiang Chen, Menghsuan Cheng, Polen Liu   +14 more
wiley   +1 more source