Results 31 to 40 of about 148,312 (268)

Benzyl-2-Acetamido-2-Deoxy-α-d-Galactopyranoside Increases Human Immunodeficiency Virus Replication and Viral Outgrowth Efficacy In Vitro

Frontiers in Immunology, 2018
Glycosylation of host and viral proteins is an important posttranslational modification needed to ensure correct function of glycoproteins. For this reason, we asked whether inhibition of O-glycosylation during human immunodeficiency virus (HIV) in vitro
Alex Olvera, Alex Olvera, Javier P. Martinez, Maria Casadellà, Anuska Llano, Míriam Rosás, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Marta Ruiz-Riol, Gemma Arsequell, Gregorio Valencia, Marc Noguera-Julian, Marc Noguera-Julian, Roger Paredes, Roger Paredes, Roger Paredes, Roger Paredes, Andreas Meyerhans, Andreas Meyerhans, Christian Brander, Christian Brander, Christian Brander   +22 more
doaj   +1 more source

Propidium Monoazide Combined With RT-qPCR Detects Infectivity of Porcine Epidemic Diarrhea Virus

Frontiers in Veterinary Science, 2022
Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) allows sensitive detection of viral particles and viruses in epidemic samples but it cannot discriminate noninfectious viruses from infectious ones.
Gong Liang, Yunzhi Long, Qianqian Li, Liu Yang, Ying Huang, Daobing Yu, Wenbo Song, Mingguang Zhou, Gaoyuan Xu, Chao Huang, Xibiao Tang   +10 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Differences in specificity, development time and virulence between two acanthocephalan parasites, infecting two cryptic species of Gammarus fossarum

Peer Community Journal
Multi-host parasites can exploit various host species that differ in abundance and susceptibility to infection, which will contribute unequally to their transmission and fitness.
Bauer, Alexandre, Develay Nguyen, Lucie, Motreuil, Sébastien, Teixeira, Maria, Debrosse, Nelly, Rigaud, Thierry   +5 more
doaj   +1 more source

Impact of season on filarial vector density and infection in Raipur City of Chhattisgarh, India [PDF]

Journal of Vector Borne Diseases, 2009
Background & objectives: Bionomics and transmission dynamics of vector population are profoundlyinfluenced by local climatic conditions. The study monitored variations in density, infection andinfectivity rates of Culex quinquefasciatus with respect to ...
Vandana Dixit, Paramanand Baghel, A.K. Gupta, P.S. Bisen, G.B.K.S. Prasad   +4 more
doaj  

Dose-response relationship of Ralstonia solanacearum and potato in greenhouse and in vitro experiments

Frontiers in Plant Science, 2022
Ralstonia solanacearum is the causative agent of bacterial wilt of potato and other vegetable crops. Contaminated irrigation water contributes to the dissemination of this pathogen but the exact concentration or biological threshold to cause an infection
Carina Eisfeld, Jack F. Schijven, Jack F. Schijven, Pieter Kastelein, Boris M. van Breukelen, Gertjan Medema, Gertjan Medema, Jouke Velstra, Peter F. M. Teunis, Jan M. van der Wolf   +9 more
doaj   +1 more source

BMT4me En Español: Multisite Feasibility and Usability Testing of a Spanish‐Language mHealth Adherence Support App for Spanish‐Speaking Caregivers of Children After Hematopoietic Stem Cell Transplantation and Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens, Madeline R. Peek, Bianca Franklin, Emre Sezgin, Melissa Beauchemin   +4 more
wiley   +1 more source

Virulence Evolution: Thinking Outside of the Host

Evolutionary Applications
The main theory of the evolution of virulence relies on a trade‐off between virulence and transmission rate. However, it has been difficult to measure the required trade‐off.
Luís M. Silva, Jacob C. Koella
doaj   +1 more source

Childhood Acute Lymphoblastic Leukemia Survival in Western Kenya: Reduction in Early Deaths and Treatment Abandonment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara, George Bogonko, Festus Njuguna, Sandra Langat, Martha Kipngetich, Dennis Njenga, Gertjan Johannes Kaspers, Terry Allen Vik   +7 more
wiley   +1 more source

Combined Effects of Elevated pCO2 and Warming Facilitate Cyanophage Infections

Frontiers in Microbiology, 2017
Elevated pCO2 and warming are generally expected to influence cyanobacterial growth, and may promote the formation of blooms. Yet, both climate change factors may also influence cyanobacterial mortality by favoring pathogens, such as viruses, which will ...
Kai Cheng, Kai Cheng, Dedmer B. Van de Waal, Xiao Ying Niu, Yi Jun Zhao   +4 more
doaj   +1 more source