A Methodology for Determining Which Diseases Warrant Care in a High-Level Containment Care Unit
Although the concept of high-level containment care (HLCC or ‘biocontainment’), dates back to 1969, the 2014−2016 outbreak of Ebola virus disease (EVD) brought with it a renewed emphasis on the use of specialized HLCC units in the care ...
Theodore J. Cieslak +3 more
doaj +1 more source
Infectivity of Norovirus GI and GII from Bottled Mineral Water during a Waterborne Outbreak, Spain
During a waterborne outbreak of norovirus in Spain, we estimated 50% illness doses for a group of exposed (secretor) persons to be 556 (95% CI 319–957) genome copies/day for norovirus GI and 2,934 (95% CI 1,683–5,044) genome copies/day for norovirus GII.
Susana Guix +11 more
doaj +1 more source
Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric +4 more
core +3 more sources
A quantitative assessment of the prion risk associated with wastewater from carcase-handling facilities [PDF]
Wastewater from facilities processing livestock that may harbor transmissible spongiform encephalopathies (TSEs) infectivity is permitted under license for application to land where susceptible livestock may have access. Several previous risk assessments
Adkin +24 more
core +1 more source
Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro [PDF]
ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid.
Deng, F. +7 more
core +3 more sources
Effects of vaccination on antibody level and duration of viral shedding in Omicron patients
Introduction: We compared the clinical characteristics of vaccinated and non-vaccinated Omicron patients in order to provide a reference for the clinical diagnosis and treatment of coronavirus disease 2019 (COVID-19).
Zhen Wan +7 more
doaj +1 more source
Propidium Monoazide Combined With RT-qPCR Detects Infectivity of Porcine Epidemic Diarrhea Virus
Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) allows sensitive detection of viral particles and viruses in epidemic samples but it cannot discriminate noninfectious viruses from infectious ones.
Gong Liang +10 more
doaj +1 more source
The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host [PDF]
Bardet–Biedl syndrome (BBS) is a human genetic disorder with a spectrum of symptoms caused by primary cilium dysfunction. The disease is caused by mutations in one of at least 17 identified genes, of which seven encode subunits of the BBSome, a protein ...
Doehl, Johannes +6 more
core +1 more source
Ralstonia solanacearum is the causative agent of bacterial wilt of potato and other vegetable crops. Contaminated irrigation water contributes to the dissemination of this pathogen but the exact concentration or biological threshold to cause an infection
Carina Eisfeld +9 more
doaj +1 more source
Respiratory infection complicating HIV infection [PDF]
Respiratory infections remain a major cause of morbidity among HIV-infected persons. Thus, knowledge of recent advances regarding HIV-associated opportunistic pneumonias is crucial for optimal care of HIV-infected persons.Bacterial pneumonia is the most common HIV-associated opportunistic pneumonia in the USA and its incidence remains appreciable ...
J Lucian, Davis +2 more
openaire +2 more sources

