Results 51 to 60 of about 1,895,431 (338)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Entropic Inference

open access: yes, 2010
In this tutorial we review the essential arguments behing entropic inference. We focus on the epistemological notion of information and its relation to the Bayesian beliefs of rational agents.
Caticha, Ariel
core   +1 more source

Inferring Trust

open access: yes, 2005
In this paper we discuss Liau's logic of Belief, Inform and Trust (BIT), which captures the use of trust to infer beliefs from acquired information. However, the logic does not capture the derivation of trust from other notions. We therefore suggest the following two extensions.
Dastani, Mehdi   +3 more
openaire   +7 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Clausal Coordination in Gã: The Case of nì †

open access: yesLanguages, 2018
This paper analyses the communicative functions of the Gã (Niger–Congo, Kwa branch) clausal connective nì, roughly corresponding to English ‘and’, drawing on Wilson and Sperber’s (1995; 2004) relevance theory.
Mark Nartey
doaj   +1 more source

Evidence and Inference [PDF]

open access: yesPhilosophy and Phenomenological Research, 2016
I articulate a functional characterisation of the concept of evidence, according to which evidence is that which allows us to make inferences that extend our knowledge. This entails Williamson's equation of knowledge with evidence.
openaire   +6 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

An Easy to Interpret Diagnostic for Approximate Inference: Symmetric Divergence Over Simulations [PDF]

open access: yesarXiv, 2021
It is important to estimate the errors of probabilistic inference algorithms. Existing diagnostics for Markov chain Monte Carlo methods assume inference is asymptotically exact, and are not appropriate for approximate methods like variational inference or Laplace's method.
arxiv  

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